Title |
An observational study of the discrediting of COX-2 NSAIDs in Australia: Vioxx or class effect?
|
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Published in |
BMC Public Health, November 2011
|
DOI | 10.1186/1471-2458-11-892 |
Pubmed ID | |
Authors |
Lynne Parkinson, Xenia Doljagore, Richard Gibson, Evan Doran, Lisa Notley, Jenny Stewart Williams, Paul Kowal, Julie E Byles |
Abstract |
When a medicine such as rofecoxib (Vioxx) is withdrawn, or a whole class of medicines discredited such as the selective COX-2 inhibitors (COX-2s), follow-up of impacts at consumer level can be difficult and costly. The Australian Longitudinal Study on Women's Health provides a rare opportunity to examine individual consumer medicine use following a major discrediting event, the withdrawal of rofecoxib and issuing of safety warnings on the COX-2 class of medicines. The overall objective of this paper was to examine the impact of this discrediting event on dispensing of the COX-2 class of medicines, by describing medicine switching behaviours of older Australian women using rofecoxib in September 2004; the uptake of other COX-2s; and the characteristics of women who continued using a COX-2. |
X Demographics
Geographical breakdown
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 3 | 17% |
Other | 2 | 11% |
Student > Bachelor | 2 | 11% |
Researcher | 2 | 11% |
Student > Master | 1 | 6% |
Other | 1 | 6% |
Unknown | 7 | 39% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 3 | 17% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 11% |
Medicine and Dentistry | 2 | 11% |
Biochemistry, Genetics and Molecular Biology | 1 | 6% |
Psychology | 1 | 6% |
Other | 3 | 17% |
Unknown | 6 | 33% |