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The LINC Complex

Overview of attention for book
Cover of 'The LINC Complex'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 EM Tomography of Meiotic LINC Complexes
  3. Altmetric Badge
    Chapter 2 Recombinant Purification of the Periplasmic Portion of the LINC Complex
  4. Altmetric Badge
    Chapter 3 Analysis of High Molecular Weight Isoforms of Nesprin-1 and Nesprin-2 with Vertical Agarose Gel Electrophoresis
  5. Altmetric Badge
    Chapter 4 Analysis of Nesprin-2 Interaction with Its Binding Partners and Actin
  6. Altmetric Badge
    Chapter 5 Interactions of Nesprin-4-Containing LINC Complexes in Outer Hair Cells Explored by BioID
  7. Altmetric Badge
    Chapter 6 Using Nesprin Tension Sensors to Measure Force on the LINC Complex
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    Chapter 7 Analyzing Mechanotransduction Through the LINC Complex in Isolated Nuclei
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    Chapter 8 Direct Force Probe for Nuclear Mechanics
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    Chapter 9 Centrifugal Displacement of Nuclei in Adherent Cells to Study LINC Complex-Dependent Mechanisms of Homeostatic Nuclear Positioning
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    Chapter 10 Assembly and Use of a Microfluidic Device to Study Cell Migration in Confined Environments
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    Chapter 11 Investigating LINC Complex Protein Homo-oligomerization in the Nuclear Envelopes of Living Cells Using Fluorescence Fluctuation Spectroscopy
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    Chapter 12 Functional Analysis of the Yeast LINC Complex Using Fluctuation Spectroscopy and Super-Resolution Imaging
  14. Altmetric Badge
    Chapter 13 Genetic Analysis of Nuclear Migration and Anchorage to Study LINC Complexes During Development of Caenorhabditis elegans
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    Chapter 14 High-Resolution Imaging Methods to Analyze LINC Complex Function During Drosophila Muscle Development
  16. Altmetric Badge
    Chapter 15 Computational Methods for Studying the Plant Nucleus
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    Chapter 16 Investigation of Nuclear Periphery Protein Interactions in Plants Using the Membrane Yeast Two-Hybrid (MbY2H) System
  18. Altmetric Badge
    Chapter 17 Immunolabeling Protocols for Studying Meiosis in Plant Mutants Defective for Nuclear Envelope Components
  19. Altmetric Badge
    Chapter 18 Generation and Analysis of Striated Muscle Selective LINC Complex Protein Mutant Mice
  20. Altmetric Badge
    Chapter 19 An In Vitro System to Measure the Positioning, Stiffness, and Rupture of the Nucleus in Skeletal Muscle
  21. Altmetric Badge
    Chapter 20 Functional Analysis of LINC Complexes in the Skin
  22. Altmetric Badge
    Chapter 21 Detection of SUN1 Splicing Variants at the mRNA and Protein Levels in Cancer
  23. Altmetric Badge
    Chapter 22 Next-Generation Sequencing and Mutational Analysis: Implications for Genes Encoding LINC Complex Proteins
Attention for Chapter 13: Genetic Analysis of Nuclear Migration and Anchorage to Study LINC Complexes During Development of Caenorhabditis elegans
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Chapter title
Genetic Analysis of Nuclear Migration and Anchorage to Study LINC Complexes During Development of Caenorhabditis elegans
Chapter number 13
Book title
The LINC Complex
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-8691-0_13
Pubmed ID
Book ISBNs
978-1-4939-8690-3, 978-1-4939-8691-0
Authors

Fridolfsson, Heidi N, Herrera, Leslie A, Brandt, James N, Cain, Natalie E, Hermann, Greg J, Starr, Daniel A, Heidi N. Fridolfsson, Leslie A. Herrera, James N. Brandt, Natalie E. Cain, Greg J. Hermann, Daniel A. Starr

Abstract

Studying nuclear positioning in developing tissues of the model nematode Caenorhabditis elegans greatly contributed to the discovery of SUN and KASH proteins and the formation of the LINC model. Such studies continue to make important contributions into both how LINC complexes are regulated and how defects in LINC components disrupt normal development. The methods described explain how to observe and quantify the following: nuclear migration in embryonic dorsal hypodermal cells, nuclear migration through constricted spaces in larval P cells, nuclear positioning in the embryonic intestinal primordia, and nuclear anchorage in syncytial hypodermal cells. These methods will allow others to employ nuclear positioning in C. elegans as a model to further explore LINC complex regulation and function.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 50%
Professor 1 13%
Student > Postgraduate 1 13%
Other 1 13%
Unknown 1 13%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 2 25%
Business, Management and Accounting 1 13%
Agricultural and Biological Sciences 1 13%
Design 1 13%
Unknown 3 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 August 2018.
All research outputs
#14,423,597
of 23,100,534 outputs
Outputs from Methods in molecular biology
#4,242
of 13,208 outputs
Outputs of similar age
#240,896
of 442,691 outputs
Outputs of similar age from Methods in molecular biology
#432
of 1,499 outputs
Altmetric has tracked 23,100,534 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,208 research outputs from this source. They receive a mean Attention Score of 3.4. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 442,691 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,499 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.