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Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited

Overview of attention for article published in Trials, November 2011
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Title
Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited
Published in
Trials, November 2011
DOI 10.1186/1745-6215-12-252
Pubmed ID
Authors

Peter Sandercock, Richard Lindley, Joanna Wardlaw, Martin Dennis, Karen Innes, Geoff Cohen, Will Whiteley, David Perry, Vera Soosay, David Buchanan, Graham Venables, Anna Czlonkowska, Adam Kobayashi, Eivind Berge, Karsten Bruins Slot, Veronica Murray, Andre Peeters, Graeme J Hankey, Karl Matz, Michael Brainin, Stefano Ricci, Teresa A Cantisani, Gordon Gubitz, Stephen J Phillips, Arauz Antonio, Manuel Correia, Phillippe Lyrer, Ingrid Kane, Erik Lundstrom, the IST-3 collaborative group

Abstract

Intravenous recombinant tissue plasminogen activator (rtPA) is approved in Europe for use in patients with acute ischaemic stroke who meet strictly defined criteria. IST-3 sought to improve the external validity and precision of the estimates of the overall treatment effects (efficacy and safety) of rtPA in acute ischaemic stroke, and to determine whether a wider range of patients might benefit.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 3 3%
Poland 1 <1%
South Africa 1 <1%
Switzerland 1 <1%
Unknown 96 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 18%
Other 11 11%
Student > Ph. D. Student 11 11%
Student > Bachelor 11 11%
Student > Postgraduate 11 11%
Other 25 25%
Unknown 15 15%
Readers by discipline Count As %
Medicine and Dentistry 53 52%
Biochemistry, Genetics and Molecular Biology 5 5%
Neuroscience 5 5%
Agricultural and Biological Sciences 5 5%
Nursing and Health Professions 3 3%
Other 11 11%
Unknown 20 20%