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Detection of autoantibodies to citrullinated BiP in rheumatoid arthritis patients and pro-inflammatory role of citrullinated BiP in collagen-induced arthritis

Overview of attention for article published in Arthritis Research & Therapy, November 2011
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Title
Detection of autoantibodies to citrullinated BiP in rheumatoid arthritis patients and pro-inflammatory role of citrullinated BiP in collagen-induced arthritis
Published in
Arthritis Research & Therapy, November 2011
DOI 10.1186/ar3520
Pubmed ID
Authors

Hirofumi Shoda, Keishi Fujio, Mihoko Shibuya, Tomohisa Okamura, Shuji Sumitomo, Akiko Okamoto, Tetsuji Sawada, Kazuhiko Yamamoto

Abstract

Anti-citrullinated protein/peptide antibodies (ACPAs) are highly specific to rheumatoid arthritis (RA) patients and are thought to have a close relationship with the pathogenesis of arthritis. Several proteins, including fibrinogen, vimentin, and alpha-enolase, were reported as ACPA-target antigens, and their importance in RA pathogenesis was widely proposed. We identified citrullinated immunoglobulin binding protein (citBiP) as another ACPA target in RA patients and examined its pro-inflammatory role in arthritis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Sweden 1 2%
Germany 1 2%
Unknown 53 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 21%
Researcher 11 20%
Student > Bachelor 6 11%
Student > Master 4 7%
Other 3 5%
Other 8 14%
Unknown 12 21%
Readers by discipline Count As %
Medicine and Dentistry 17 30%
Agricultural and Biological Sciences 10 18%
Biochemistry, Genetics and Molecular Biology 8 14%
Immunology and Microbiology 6 11%
Nursing and Health Professions 2 4%
Other 1 2%
Unknown 12 21%