↓ Skip to main content

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression

Overview of attention for article published in Genome Medicine, November 2015
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

Mentioned by

twitter
13 X users
facebook
2 Facebook pages

Citations

dimensions_citation
63 Dimensions

Readers on

mendeley
149 Mendeley
citeulike
1 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression
Published in
Genome Medicine, November 2015
DOI 10.1186/s13073-015-0240-5
Pubmed ID
Authors

Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle

Abstract

Human cancer cell lines are an important resource for research and drug development. However, the available annotations of cell lines are sparse, incomplete, and distributed in multiple repositories. Re-analyzing publicly available raw RNA-Seq data, we determined the human leukocyte antigen (HLA) type and abundance, identified expressed viruses and calculated gene expression of 1,082 cancer cell lines. Using the determined HLA types, public databases of cell line mutations, and existing HLA binding prediction algorithms, we predicted antigenic mutations in each cell line. We integrated the results into a comprehensive knowledgebase. Using the Django web framework, we provide an interactive user interface with advanced search capabilities to find and explore cell lines and an application programming interface to extract cell line information. The portal is available at http://celllines.tron-mainz.de .

X Demographics

X Demographics

The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 149 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 148 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 34 23%
Student > Ph. D. Student 23 15%
Student > Master 12 8%
Student > Bachelor 11 7%
Other 11 7%
Other 25 17%
Unknown 33 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 35 23%
Agricultural and Biological Sciences 24 16%
Immunology and Microbiology 15 10%
Medicine and Dentistry 15 10%
Computer Science 4 3%
Other 19 13%
Unknown 37 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 July 2022.
All research outputs
#4,232,519
of 24,124,090 outputs
Outputs from Genome Medicine
#845
of 1,493 outputs
Outputs of similar age
#66,787
of 394,940 outputs
Outputs of similar age from Genome Medicine
#16
of 42 outputs
Altmetric has tracked 24,124,090 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,493 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.6. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 394,940 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.