Title |
Water spray-induced grooming is negatively correlated with depressive behavior in the forced swimming test in rats
|
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Published in |
The Journal of Physiological Sciences, November 2015
|
DOI | 10.1007/s12576-015-0424-1 |
Pubmed ID | |
Authors |
Noboru Shiota, Kimiya Narikiyo, Akira Masuda, Shuji Aou |
Abstract |
Rodents show grooming, a typical self-care behavior, under stress and non-stress conditions. Previous studies revealed that grooming under stress conditions such as the open-field test (OFT) or the elevated plus-maze test (EPM) is associated with anxiety, but the roles of grooming under non-stress conditions are not well understood. Here, we examined spray-induced grooming as a model of grooming under a non-stress condition to investigate the relationship between this grooming and depression-like behavior in the forced swim test (FST) and tail suspension test, and we compared spray-induced grooming with OFT- and EPM-induced grooming. The main finding was that the duration of spray-induced grooming, but not that of OFT/EPM-induced grooming, was negatively correlated with the duration of immobility in the FST, an index of depression-like behavior. The results suggest that spray-induced grooming is functionally different from the grooming in the OFT and EPM and is related to reduction of depressive behavior. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 46 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 10 | 22% |
Student > Ph. D. Student | 9 | 20% |
Researcher | 5 | 11% |
Student > Doctoral Student | 3 | 7% |
Student > Master | 3 | 7% |
Other | 5 | 11% |
Unknown | 11 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Neuroscience | 11 | 24% |
Biochemistry, Genetics and Molecular Biology | 4 | 9% |
Psychology | 3 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
Agricultural and Biological Sciences | 2 | 4% |
Other | 9 | 20% |
Unknown | 15 | 33% |