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Preventive Effect of Preoperative Vitamin D Supplementation on Postoperative Atrial Fibrillation

Overview of attention for article published in Brazilian Journal of Cardiovascular Surgery, January 2018
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Title
Preventive Effect of Preoperative Vitamin D Supplementation on Postoperative Atrial Fibrillation
Published in
Brazilian Journal of Cardiovascular Surgery, January 2018
DOI 10.21470/1678-9741-2018-0014
Pubmed ID
Authors

Levent Cerit, Barçın Özcem, Zeynep Cerit, Hamza Duygu

Abstract

To assess the relationship between preoperative vitamin D (vitD) supplementation and the development of postoperative atrial fibrillation (POAF). The study group consisted of 328 consecutive patients. The ınfluence of preoperative vitD supplementation on POAF was reviewed in 136 patients who underwent coronary artery bypass graft surgery with vitD insufficiency (n=80) and vitD deficiency (n=56). Patients were assigned to receive either oral vitD (50.000 U) (treatment group, n=68) or not (control group, n=68) 48 hours before surgery. Patients were followed up during hospitalisation process with respect to POAF. There was no significant difference between treatment and control groups with regards to age, gender, diabetes mellitus, smoking history, chronic obstructive pulmonary disease, left atrial diameter, and biochemical parameters. Also, there was no significant difference between these groups with regards to mean vitD level on both insufficiency and deficiency patients (24.6±3.7 vs. 24.9±3.9 ng/ml P=0.837, 11.4±4.9 vs. 10.9±5.2 ng/ml P=0.681, respectively). Although the occurrence of POAF was not significantly different among treatment and control groups in patients with vitD insufficiency (31% vs. 33% P=0.538), there was a significant difference between the two groups regarding to POAF in patients with vitD deficiency (18% vs. 29% P=0.02). Although preoperative vitD supplementation was not found to be associated with prevention of POAF in patients with vitD insufficiency, it was found to be strongly associated with prevention of POAF in those with vitD deficiency.

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Geographical breakdown

Country Count As %
Unknown 53 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 19%
Student > Master 10 19%
Professor > Associate Professor 4 8%
Student > Ph. D. Student 3 6%
Student > Postgraduate 2 4%
Other 9 17%
Unknown 15 28%
Readers by discipline Count As %
Medicine and Dentistry 20 38%
Nursing and Health Professions 7 13%
Pharmacology, Toxicology and Pharmaceutical Science 5 9%
Agricultural and Biological Sciences 2 4%
Computer Science 2 4%
Other 2 4%
Unknown 15 28%