Title |
Curating the innate immunity interactome
|
---|---|
Published in |
BMC Systems Biology, August 2010
|
DOI | 10.1186/1752-0509-4-117 |
Pubmed ID | |
Authors |
David J Lynn, Calvin Chan, Misbah Naseer, Melissa Yau, Raymond Lo, Anastasia Sribnaia, Giselle Ring, Jaimmie Que, Kathleen Wee, Geoffrey L Winsor, Matthew R Laird, Karin Breuer, Amir K Foroushani, Fiona SL Brinkman, Robert EW Hancock |
Abstract |
The innate immune response is the first line of defence against invading pathogens and is regulated by complex signalling and transcriptional networks. Systems biology approaches promise to shed new light on the regulation of innate immunity through the analysis and modelling of these networks. A key initial step in this process is the contextual cataloguing of the components of this system and the molecular interactions that comprise these networks. InnateDB (http://www.innatedb.com) is a molecular interaction and pathway database developed to facilitate systems-level analyses of innate immunity. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 4 | 3% |
United States | 4 | 3% |
Italy | 2 | 1% |
Brazil | 2 | 1% |
Austria | 1 | <1% |
Switzerland | 1 | <1% |
Netherlands | 1 | <1% |
India | 1 | <1% |
Sweden | 1 | <1% |
Other | 2 | 1% |
Unknown | 115 | 86% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 35 | 26% |
Student > Ph. D. Student | 33 | 25% |
Professor > Associate Professor | 10 | 7% |
Student > Postgraduate | 9 | 7% |
Student > Master | 9 | 7% |
Other | 25 | 19% |
Unknown | 13 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 67 | 50% |
Biochemistry, Genetics and Molecular Biology | 20 | 15% |
Medicine and Dentistry | 11 | 8% |
Immunology and Microbiology | 9 | 7% |
Computer Science | 3 | 2% |
Other | 5 | 4% |
Unknown | 19 | 14% |