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A metagenome-wide association study of gut microbiota in asthma in UK adults

Overview of attention for article published in BMC Microbiology, September 2018
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#29 of 2,189)
  • High Attention Score compared to outputs of the same age (92nd percentile)

Mentioned by

blogs
1 blog
twitter
44 tweeters

Citations

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13 Dimensions

Readers on

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52 Mendeley
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Title
A metagenome-wide association study of gut microbiota in asthma in UK adults
Published in
BMC Microbiology, September 2018
DOI 10.1186/s12866-018-1257-x
Pubmed ID
Authors

Qi Wang, Fei Li, Bishan Liang, Yuhu Liang, Sijie Chen, Xiaodong Mo, Yanmei Ju, Hui Zhao, Huijue Jia, Timothy D. Spector, Hailiang Xie, Ruijin Guo

Abstract

Asthma, one of the most common chronic respiratory disorders, is associated with the hyper-activation of the T-cell subset of adaptive immunity. The gut microbiota may be involved in the development of asthma through the production of short-chain fatty acids (SCFAs), exhibiting modulatory effects on Th. So, we performed a metagenome-wide association study (MWAS) of the fecal microbiota from individuals with asthma and healthy controls. And that was the first case to resolve the relationship between asthma and microbiome among UK adults. The microbiota of the individuals with asthma consisted of fewer microbial entities than the microbiota of healthy individuals. Faecalibacterium prausnitzii, Sutterella wadsworthensis and Bacteroides stercoris were depleted in cases, whereas Clostridiums with Eggerthella lenta were over-represented in individuals with asthma. Functional analysis shows that the SCFAs might be altered in the microbiota of asthma patients. In all, the adult human gut microbiome of asthma patients is clearly different from healthy controls. The functional and taxa results showed that the change of asthma patients might related to SCFAs.

Twitter Demographics

The data shown below were collected from the profiles of 44 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 52 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 23%
Student > Master 9 17%
Researcher 9 17%
Student > Bachelor 6 12%
Other 3 6%
Other 8 15%
Unknown 5 10%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 13 25%
Immunology and Microbiology 9 17%
Medicine and Dentistry 6 12%
Agricultural and Biological Sciences 5 10%
Computer Science 3 6%
Other 10 19%
Unknown 6 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 30. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 October 2019.
All research outputs
#640,881
of 14,579,947 outputs
Outputs from BMC Microbiology
#29
of 2,189 outputs
Outputs of similar age
#21,373
of 271,037 outputs
Outputs of similar age from BMC Microbiology
#1
of 1 outputs
Altmetric has tracked 14,579,947 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,189 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 271,037 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them