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The complement system in glioblastoma multiforme

Overview of attention for article published in Acta Neuropathologica Communications, September 2018
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Title
The complement system in glioblastoma multiforme
Published in
Acta Neuropathologica Communications, September 2018
DOI 10.1186/s40478-018-0591-4
Pubmed ID
Authors

T. A. M. Bouwens van der Vlis, J. M. Kros, D. A. M. Mustafa, R. T. A. van Wijck, L. Ackermans, P. M. van Hagen, P. J. van der Spek

Abstract

The human complement system is represents the main effector arm of innate immunity and its ambivalent function in cancer has been subject of ongoing dispute. Glioma stem-like cells (GSC) residing in specific niches within glioblastomas (GBM) are capable of self-renewal and tumor proliferation. Recent data are indicative of the influence of the complement system on the maintenance of these cells. It appears that the role of the complement system in glial tumorigenesis, particularly its influence on GSC niches and GSC maintenance, is significant and warrants further exploration for therapeutic interventions.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 49 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 12%
Student > Doctoral Student 6 12%
Student > Bachelor 6 12%
Researcher 4 8%
Student > Master 4 8%
Other 8 16%
Unknown 15 31%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 22%
Medicine and Dentistry 6 12%
Immunology and Microbiology 3 6%
Neuroscience 2 4%
Chemistry 2 4%
Other 6 12%
Unknown 19 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 September 2018.
All research outputs
#15,018,906
of 23,103,436 outputs
Outputs from Acta Neuropathologica Communications
#1,127
of 1,398 outputs
Outputs of similar age
#201,781
of 337,668 outputs
Outputs of similar age from Acta Neuropathologica Communications
#28
of 37 outputs
Altmetric has tracked 23,103,436 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,398 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.8. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 337,668 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.