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X-Chromosome Inactivation

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Cover of 'X-Chromosome Inactivation'

Table of Contents

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    Book Overview
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    Chapter 1 Screening for Factors Involved in X Chromosome Inactivation Using Haploid ESCs
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    Chapter 2 Unbiased Genetic Screen to Identify Factors Involved in X-Chromosome Inactivation Using a Pooled Bar-Coded shRNA Library
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    Chapter 3 ChIRP-MS: RNA-Directed Proteomic Discovery
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    Chapter 4 Manipulation of Xist Imprinting in Mouse Preimplantation Embryos
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    Chapter 5 Somatic Cell Nuclear Transfer in Mice: Basic Protocol and Its Modification for Correcting X Chromosome Inactivation Status
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    Chapter 6 Live Imaging of Xist RNA
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    Chapter 7 Live Imaging of X-Chromosome Inactivation and Reactivation Kinetics
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    Chapter 8 Visualizing the Dynamics of Inactive X Chromosomes in Living Cells Using Antibody-Based Fluorescent Probes
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    Chapter 9 Visualization of Hidden Epitopes at the Inactive X Chromosome
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    Chapter 10 Chromosome Spread Analyses of Meiotic Sex Chromosome Inactivation
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    Chapter 11 Simultaneous RNA–DNA FISH in Mouse Preimplantation Embryos
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    Chapter 12 Combined Immunofluorescence, RNA FISH, and DNA FISH in Preimplantation Mouse Embryos
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    Chapter 13 RNA-FISH and Immunofluorescence of Mouse Preimplantation and Postimplantation Embryos
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    Chapter 14 Experimental Analysis of Imprinted Mouse X-Chromosome Inactivation
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    Chapter 15 X-Chromosome Inactivation and Escape from X Inactivation in Mouse
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    Chapter 16 Practical Analysis of Hi-C Data: Generating A/B Compartment Profiles
Attention for Chapter 15: X-Chromosome Inactivation and Escape from X Inactivation in Mouse
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Chapter title
X-Chromosome Inactivation and Escape from X Inactivation in Mouse
Chapter number 15
Book title
X-Chromosome Inactivation
Published in
Methods in molecular biology, September 2018
DOI 10.1007/978-1-4939-8766-5_15
Pubmed ID
Book ISBNs
978-1-4939-8765-8, 978-1-4939-8766-5
Authors

Wenxiu Ma, Giancarlo Bonora, Joel B. Berletch, Xinxian Deng, William S. Noble, Christine M. Disteche, Ma, Wenxiu, Bonora, Giancarlo, Berletch, Joel B., Deng, Xinxian, Noble, William S., Disteche, Christine M.

Abstract

X chromosome inactivation silences one X chromosome in female mammals. However, this silencing is incomplete, and some genes escape X inactivation. We describe methods to determine the chromosome-wide X inactivation status of genes in tissues or cell lines derived from mice using a combination of skewing of X inactivation and allele-specific analyses of gene expression based on RNA-seq.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 32%
Researcher 4 18%
Student > Master 2 9%
Student > Bachelor 2 9%
Unspecified 1 5%
Other 2 9%
Unknown 4 18%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 45%
Immunology and Microbiology 3 14%
Neuroscience 2 9%
Agricultural and Biological Sciences 1 5%
Medicine and Dentistry 1 5%
Other 1 5%
Unknown 4 18%