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RT @DanielJDrucker: @CaATiER_Chop_ER Data from some mouse studies suggests loss of GIP action in beta cells reduces insulin and adipose tis…
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@CaATiER_Chop_ER Data from some mouse studies suggests loss of GIP action in beta cells reduces insulin and adipose tissue mass. It is also possible that sustained GIPR agonism desensitizes the GIPR and in effect, converts to a loss of GIPR phenotype. More
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Several years ago, as a postdoc, @oJCampbellLab set out to study the metabolic biology of the GIPR, starting in #iislets Jon found that loss of the GIPR indirectly impacted mouse adipose tissue through reduced #insulin https://t.co/XJZnDG8emI
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RT @DanielJDrucker: An update on studies from our lab several years ago, revealing #islet TCF7 expression was downstream of GIP action. Mul…