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Mendeley readers
Attention Score in Context
| Title |
The Role of the Brain's Endocannabinoid System in Pain and Its Modulation by Stress.
|
|---|---|
| Published in |
International review of neurobiology, January 2015
|
| DOI | 10.1016/bs.irn.2015.10.003 |
| Pubmed ID | |
| Authors |
Corcoran, Louise, Roche, Michelle, Finn, David P |
| Abstract |
Stress has a complex, bidirectional modulatory influence on pain. Stress may either reduce (stress-induced analgesia) or exacerbate (stress-induced hyperalgesia) pain depending on the nature, duration, and intensity of the stressor. The endogenous cannabinoid (endocannabinoid) system is present throughout the neuroanatomical pathways that mediate and modulate responses to painful stimuli. The specific role of the endocannabinoid system in the brain in pain and the modulation of pain by stress is reviewed herein. We first provide a brief overview of the endocannabinoid system, followed by a review of the evidence that the brain's endocannabinoid system modulates pain. We provide a comprehensive evaluation of the role of the endocannabinoid system supraspinally, and particularly in the rostral ventromedial medulla, periaqueductal gray, amygdala, and prefrontal cortex, in pain, stress-induced analgesia, and stress-induced hyperalgesia. Increased understanding of endocannabinoid-mediated regulation of pain and its modulation by stress will inform the development of novel therapeutic approaches for pain and its comorbidity with stress-related disorders. |
Mendeley readers
The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 107 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 17 | 16% |
| Researcher | 15 | 14% |
| Student > Bachelor | 13 | 12% |
| Student > Master | 11 | 10% |
| Student > Doctoral Student | 9 | 8% |
| Other | 20 | 19% |
| Unknown | 22 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 20 | 19% |
| Medicine and Dentistry | 19 | 18% |
| Psychology | 9 | 8% |
| Biochemistry, Genetics and Molecular Biology | 8 | 7% |
| Agricultural and Biological Sciences | 7 | 7% |
| Other | 16 | 15% |
| Unknown | 28 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 December 2015.
All research outputs
#18,683,314
of 23,149,216 outputs
Outputs from International review of neurobiology
#536
of 647 outputs
Outputs of similar age
#257,656
of 354,754 outputs
Outputs of similar age from International review of neurobiology
#39
of 47 outputs
Altmetric has tracked 23,149,216 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 647 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.1. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 354,754 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.