Title |
Riboflavin prophylaxis in pediatric and adolescent migraine
|
---|---|
Published in |
The Journal of Headache and Pain, August 2009
|
DOI | 10.1007/s10194-009-0142-2 |
Pubmed ID | |
Authors |
Maria Condò, Annio Posar, Annalisa Arbizzani, Antonia Parmeggiani |
Abstract |
Migraine is a common disorder in childhood and adolescence. Studies on adults show the effectiveness and tolerability of riboflavin in migraine prevention, while data on children are scarce. This retrospective study reports on our experience of using riboflavin for migraine prophylaxis in 41 pediatric and adolescent patients, who received 200 or 400 mg/day single oral dose of riboflavin for 3, 4 or 6 months. Attack frequency and intensity decreased (P < 0.01) during treatment, and these results were confirmed during the follow-up. A large number of patients (77.1%) reported that abortive drugs were effective for controlling ictal events. During the follow-up, 68.4% of cases had a 50% or greater reduction in frequency of attacks and 21.0% in intensity. Two patients had vomiting and increased appetite, respectively, most likely for causes unrelated to the use of riboflavin. In conclusion, riboflavin seems to be a well-tolerated, effective, and low-cost prophylactic treatment in children and adolescents suffering from migraine. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Canada | 2 | 67% |
Colombia | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Korea, Republic of | 1 | 1% |
Unknown | 91 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 12% |
Student > Master | 11 | 12% |
Student > Bachelor | 11 | 12% |
Other | 8 | 9% |
Student > Doctoral Student | 7 | 8% |
Other | 18 | 20% |
Unknown | 26 | 28% |
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---|---|---|
Medicine and Dentistry | 37 | 40% |
Nursing and Health Professions | 8 | 9% |
Agricultural and Biological Sciences | 7 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 4% |
Biochemistry, Genetics and Molecular Biology | 3 | 3% |
Other | 7 | 8% |
Unknown | 26 | 28% |