| Chapter title |
MicroRNAs as Regulators of Prostate Cancer Metastasis
|
|---|---|
| Chapter number | 5 |
| Book title |
Cell & Molecular Biology of Prostate Cancer
|
| Published in |
Advances in experimental medicine and biology, September 2018
|
| DOI | 10.1007/978-3-319-95693-0_5 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-995692-3, 978-3-31-995693-0
|
| Authors |
Divya Bhagirath, Thao Ly Yang, Rajvir Dahiya, Sharanjot Saini, Bhagirath, Divya, Yang, Thao Ly, Dahiya, Rajvir, Saini, Sharanjot |
| Abstract |
Prostate cancer causes significant morbidity in men and metastatic disease is a major cause of cancer related deaths. Prostate metastasis is controlled by various cellular intrinsic and extrinsic factors, which are often under the regulatory control of various metastasis-associated genes. Given the dynamic nature of metastatic cancer cells, the various factors controlling this process are themselves regulated by microRNAs which are small non-coding RNAs. Significant research work has shown differential microRNA expression in primary and metastatic prostate cancer suggesting their importance in prostate pathogenesis. We will review the roles of different microRNAs in controlling the various steps in prostate metastasis. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 11 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 4 | 36% |
| Student > Bachelor | 2 | 18% |
| Student > Doctoral Student | 1 | 9% |
| Student > Master | 1 | 9% |
| Student > Postgraduate | 1 | 9% |
| Other | 0 | 0% |
| Unknown | 2 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 2 | 18% |
| Medicine and Dentistry | 2 | 18% |
| Immunology and Microbiology | 2 | 18% |
| Biochemistry, Genetics and Molecular Biology | 1 | 9% |
| Unknown | 4 | 36% |