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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The interplay of extracellular matrix and microbiome in urothelial bladder cancer
|
|---|---|
| Published in |
Nature Reviews Urology, December 2015
|
| DOI | 10.1038/nrurol.2015.292 |
| Pubmed ID | |
| Authors |
Massimo Alfano, Filippo Canducci, Manuela Nebuloni, Massimo Clementi, Francesco Montorsi, Andrea Salonia |
| Abstract |
Many pathological changes in solid tumours are caused by the accumulation of genetic mutations and epigenetic molecular alterations. In addition, tumour progression is profoundly influenced by the environment surrounding the transformed cells. The interplay between tumour cells and their microenvironment has been recognized as one of the key determinants of cancer development and is being extensively investigated. Data suggest that both the extracellular matrix and the microbiota represent microenvironments that contribute to the onset and progression of tumours. Through the introduction of omics technologies and pyrosequencing analyses, a detailed investigation of these two microenvironments is now possible. In urological research, assessment of their dysregulation has become increasingly important to provide diagnostic, prognostic and predictive biomarkers for urothelial bladder cancer. Understanding the roles of the extracellular matrix and microbiota, two key components of the urothelial mucosa, in the sequelae of pathogenic events that occur in the development and progression of urothelial carcinomas will be important to overcome the shortcomings in current bladder cancer treatment strategies. |
X Demographics
The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 22% |
| France | 2 | 22% |
| Germany | 1 | 11% |
| Netherlands | 1 | 11% |
| United Kingdom | 1 | 11% |
| Unknown | 2 | 22% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 89% |
| Science communicators (journalists, bloggers, editors) | 1 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 153 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Germany | 1 | <1% |
| India | 1 | <1% |
| United Kingdom | 1 | <1% |
| Taiwan | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 147 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 33 | 22% |
| Student > Ph. D. Student | 23 | 15% |
| Student > Master | 21 | 14% |
| Student > Doctoral Student | 10 | 7% |
| Student > Bachelor | 9 | 6% |
| Other | 24 | 16% |
| Unknown | 33 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 36 | 24% |
| Biochemistry, Genetics and Molecular Biology | 25 | 16% |
| Agricultural and Biological Sciences | 23 | 15% |
| Immunology and Microbiology | 7 | 5% |
| Nursing and Health Professions | 4 | 3% |
| Other | 13 | 8% |
| Unknown | 45 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 November 2016.
All research outputs
#6,208,098
of 24,885,505 outputs
Outputs from Nature Reviews Urology
#910
of 2,092 outputs
Outputs of similar age
#90,548
of 401,918 outputs
Outputs of similar age from Nature Reviews Urology
#25
of 70 outputs
Altmetric has tracked 24,885,505 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 2,092 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 401,918 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 70 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.