Among 34 loci previously discovered in a large international GWAS (>33k subjects) https://t.co/hTb6K6d0hw, 31/34 were nominally associated with AMD in our cohort. 11/34 reached Bonferroni-corrected significance (0.05/34).
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RT @Eric_Fauman: We've come a long way in 15 years. From neglogp of 7.4 for CFH for age related macular degeneration in 2005 to 617 in thi…
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We've come a long way in 15 years. From neglogp of 7.4 for CFH for age related macular degeneration in 2005 to 617 in this 2016 GWAS: https://t.co/ZCi4PhqxkV
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Still looking for any information on the ARMS2 locus for age-related macular degeneration. At a p-value of 1e-734 it is the strongest p-value for a disease where the causal gene is ambiguous (at least to me). https://t.co/ZCi4PhqxkV