↓ Skip to main content

Effects of vitamin D 2 or D 3 supplementation on glycaemic control and cardiometabolic risk among people at risk of…

Overview of attention for article published in Diabetes, Obesity & Metabolism, February 2016
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

Mentioned by

twitter
13 tweeters

Citations

dimensions_citation
32 Dimensions

Readers on

mendeley
68 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Effects of vitamin D 2 or D 3 supplementation on glycaemic control and cardiometabolic risk among people at risk of type 2 diabetes: results of a randomized double-blind placebo-controlled trial
Published in
Diabetes, Obesity & Metabolism, February 2016
DOI 10.1111/dom.12625
Pubmed ID
Authors

N. G. Forouhi, R. K. Menon, S. J. Sharp, N. Mannan, P. M. Timms, A. R. Martineau, A. P. Rickard, B. J. Boucher, T. A. Chowdhury, C. J. Griffiths, S. E. Greenwald, S. J. Griffin, G. A. Hitman

Abstract

Although an inverse association between 25-hydroxyvitamin D [25(OH)D] concentration and type 2 diabetes and coronary risk exists, a causal link has not been established. We investigated the effect of short-term vitamin D supplementation on cardiometabolic outcomes among individuals at increased diabetes risk. In a double-blind placebo-controlled randomised trial, 340 adults at increased type 2 diabetes risk (non-diabetic hyperglycaemia or positive diabetes risk score) were randomised to either placebo, 100,000 IU Vitamin D2 (ergocalciferol) or 100,000 IU Vitamin D3 (cholecalciferol), orally administered monthly for four months. The primary outcome was change in glycated haemoglobin (HbA1c ) between baseline and four months, adjusted for baseline. Secondary outcomes included: blood pressure, lipids, apolipoproteins, C-reactive protein, pulse wave velocity (PWV), anthropometric measures and safety of supplementation. Mean (SD) 25(OH)D2 concentration increased from 5.2 (4.1) to 53.9 (18.5) nmol/l in D2 group, and 25(OH)D3 from 45.8 (22.6) to 83.8 (22.7) nmol/l in D3 . There was no effect of vitamin D supplementation on HbA1c : D2 versus placebo: -0.51 (-1.16, 0.14) mmol/mol;p = 0.13; [-0.05% (95%CI -0.11%, 0.02%)]; D3 versus placebo: 0.19 (-0.46, 0.83) mmol/mol;p = 0.57; [0.02% (-0.04%, 0.08%)]. There were no clinically meaningful effects on secondary outcomes, except PWV [D2 versus placebo:-0.68 (-1.31, -0.05) m/s; D3 versus placebo -0.73 (-1.42, -0.03) m/s]. No important safety issues were identified. Short-term supplementation with vitamin D2 or D3 had no effect on HbA1c . The modest reduction in PWV with both D2 and D3 relative to placebo suggests a beneficial effect of vitamin D supplementation on arterial stiffness.

Twitter Demographics

The data shown below were collected from the profiles of 13 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 1%
Unknown 67 99%

Demographic breakdown

Readers by professional status Count As %
Unspecified 17 25%
Student > Master 17 25%
Researcher 5 7%
Student > Ph. D. Student 5 7%
Student > Doctoral Student 4 6%
Other 20 29%
Readers by discipline Count As %
Medicine and Dentistry 26 38%
Unspecified 19 28%
Nursing and Health Professions 13 19%
Social Sciences 4 6%
Biochemistry, Genetics and Molecular Biology 3 4%
Other 3 4%

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 July 2016.
All research outputs
#1,942,794
of 12,667,698 outputs
Outputs from Diabetes, Obesity & Metabolism
#422
of 1,820 outputs
Outputs of similar age
#60,345
of 352,152 outputs
Outputs of similar age from Diabetes, Obesity & Metabolism
#13
of 41 outputs
Altmetric has tracked 12,667,698 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,820 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.8. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,152 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.