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SOX2 expression correlates with lymph-node metastases and distant spread in right-sided colon cancer

Overview of attention for article published in BMC Cancer, December 2011
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Title
SOX2 expression correlates with lymph-node metastases and distant spread in right-sided colon cancer
Published in
BMC Cancer, December 2011
DOI 10.1186/1471-2407-11-518
Pubmed ID
Authors

Jens Neumann, Fiorina Bahr, David Horst, Lydia Kriegl, Jutta Engel, Raquel Mejías-Luque, Markus Gerhard, Thomas Kirchner, Andreas Jung

Abstract

The transcription factor SOX2, which is involved in the induction of pluripotent stem cells and contributes to colorectal carcinogenesis, is associated with a poor prognosis in colon cancer (CC). Furthermore, SOX2 is a repressor of the transcriptional activity of β-catenin in vitro. Since the majority of CC develop via an activation of the Wnt/β-catenin signalling pathway, indicated by nuclear expression of β-catenin, we wanted to investigate the expression patterns of SOX2 and β-catenin and correlate them with the occurrence of lymph node and distant metastases as indicators of malignant progression.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
China 1 1%
Luxembourg 1 1%
Unknown 68 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 23%
Researcher 15 21%
Student > Master 10 14%
Student > Bachelor 7 10%
Professor > Associate Professor 3 4%
Other 8 11%
Unknown 12 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 28%
Medicine and Dentistry 20 28%
Biochemistry, Genetics and Molecular Biology 12 17%
Immunology and Microbiology 2 3%
Nursing and Health Professions 1 1%
Other 3 4%
Unknown 13 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2011.
All research outputs
#15,239,825
of 22,659,164 outputs
Outputs from BMC Cancer
#4,098
of 8,238 outputs
Outputs of similar age
#163,388
of 242,485 outputs
Outputs of similar age from BMC Cancer
#46
of 95 outputs
Altmetric has tracked 22,659,164 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,238 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,485 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 95 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.