認知症の興奮に対するバルプロ酸製剤 Valproate preparations for agitation in dementia 2018 Oct 5;10(10):CD003945. doi: 10.1002/14651858.CD003945.pub4. PMID: 30293233; PMCID: PMC6516950. https://t.co/dRVjwo04Ne
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2- There is very little evidence to support of use of these medications for behavioral & psychological symptoms of #dementia (BPSD). Eg, no evidence of benefit w/ VPA: https://t.co/c0Qa6R51WV RCT of VPA revealed increased CNS atrophy: https://t.co/
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RT @dtmaust: Problem? They don't work. Not like "we're not sure." Rather, per the most recent Cochrane review, they shouldn't be used and…
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Problem? They don't work. Not like "we're not sure." Rather, per the most recent Cochrane review, they shouldn't be used and patients might be worse off. https://t.co/0f5g9BP64f