Title |
Peroxisome proliferator-activated receptor α (PPARα) mRNA expression in human hepatocellular carcinoma tissue and non-cancerous liver tissue
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Published in |
World Journal of Surgical Oncology, December 2011
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DOI | 10.1186/1477-7819-9-167 |
Pubmed ID | |
Authors |
Tsuyoshi Kurokawa, Yoshiharu Shimomura, Gustavo Bajotto, Katsuhiro Kotake, Takashi Arikawa, Nobuhiro Ito, Akira Yasuda, Hiroshi Nagata, Toshiaki Nonami, Kazuo Masuko |
Abstract |
Peroxisome proliferator-activated receptor α (PPARα) regulates lipid metabolism in the liver. It is unclear, however, how this receptor changes in liver cancer tissue. On the other hand, mouse carcinogenicity studies showed that PPARα is necessary for the development of liver cancer induced by peroxisome proliferators, and the relationship between PPARα and the development of liver cancer have been the focus of considerable attention. There have been no reports, however, demonstrating that PPARα is involved in the development of human liver cancer. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 16 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 3 | 19% |
Student > Doctoral Student | 2 | 13% |
Researcher | 2 | 13% |
Student > Postgraduate | 2 | 13% |
Student > Ph. D. Student | 2 | 13% |
Other | 3 | 19% |
Unknown | 2 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 4 | 25% |
Medicine and Dentistry | 4 | 25% |
Agricultural and Biological Sciences | 3 | 19% |
Nursing and Health Professions | 1 | 6% |
Chemistry | 1 | 6% |
Other | 0 | 0% |
Unknown | 3 | 19% |