↓ Skip to main content

Assessing the potential impact of artemisinin and partner drug resistance in sub-Saharan Africa

Overview of attention for article published in Malaria Journal, January 2016
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • High Attention Score compared to outputs of the same age and source (82nd percentile)

Mentioned by

twitter
7 tweeters

Citations

dimensions_citation
42 Dimensions

Readers on

mendeley
102 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Assessing the potential impact of artemisinin and partner drug resistance in sub-Saharan Africa
Published in
Malaria Journal, January 2016
DOI 10.1186/s12936-015-1075-7
Pubmed ID
Authors

Hannah C. Slater, Jamie T. Griffin, Azra C. Ghani, Lucy C. Okell

Abstract

Artemisinin and partner drug resistant malaria parasites have emerged in Southeast Asia. If resistance were to emerge in Africa it could have a devastating impact on malaria-related morbidity and mortality. This study estimates the potential impact of artemisinin and partner drug resistance on disease burden in Africa if it were to emerge. Using data from Asia and Africa, five possible artemisinin and partner drug resistance scenarios are characterized. An individual-based malaria transmission model is used to estimate the impact of each resistance scenario on clinical incidence and parasite prevalence across Africa. Artemisinin resistance is characterized by slow parasite clearance and partner drug resistance is associated with late clinical failure or late parasitological failure. Scenarios with high levels of recrudescent infections resulted in far greater increases in clinical incidence compared to scenarios with high levels of slow parasite clearance. Across Africa, it is estimated that artemisinin and partner drug resistance at levels similar to those observed in Oddar Meanchey province in Cambodia could result in an additional 78 million cases over a 5 year period, a 7 % increase in cases compared to a scenario with no resistance. A scenario with high levels of slow clearance but no recrudescence resulted in an additional 10 million additional cases over the same period. Artemisinin resistance is potentially a more pressing concern than partner drug resistance due to the lack of viable alternatives. However, it is predicted that a failing partner drug will result in greater increases in malaria cases and morbidity than would be observed from artemisinin resistance only.

Twitter Demographics

The data shown below were collected from the profiles of 7 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Netherlands 1 <1%
Vietnam 1 <1%
Unknown 99 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 30 29%
Student > Ph. D. Student 20 20%
Researcher 13 13%
Student > Bachelor 12 12%
Student > Doctoral Student 4 4%
Other 13 13%
Unknown 10 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 24 24%
Medicine and Dentistry 20 20%
Biochemistry, Genetics and Molecular Biology 10 10%
Immunology and Microbiology 6 6%
Chemistry 6 6%
Other 21 21%
Unknown 15 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2016.
All research outputs
#1,311,019
of 7,099,316 outputs
Outputs from Malaria Journal
#503
of 2,398 outputs
Outputs of similar age
#68,226
of 305,300 outputs
Outputs of similar age from Malaria Journal
#30
of 180 outputs
Altmetric has tracked 7,099,316 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,398 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,300 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 180 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.