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Spermatogonial stem cells as a therapeutic alternative for fertility preservation of prepubertal boys

Overview of attention for article published in Einstein (São Paulo), December 2015
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About this Attention Score

  • Among the highest-scoring outputs from this source (#35 of 215)
  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

twitter
1 tweeter
wikipedia
1 Wikipedia page

Citations

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12 Dimensions

Readers on

mendeley
42 Mendeley
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Title
Spermatogonial stem cells as a therapeutic alternative for fertility preservation of prepubertal boys
Published in
Einstein (São Paulo), December 2015
DOI 10.1590/s1679-45082015rb3456
Pubmed ID
Authors

Andrea Giannotti Galuppo

Abstract

Spermatogonial stem cells, which exist in the testicles since birth, are progenitors cells of male gametes. These cells are critical for the process of spermatogenesis, and not able to produce mature sperm cells before puberty due to their dependency of hormonal stimuli. This characteristic of the reproductive system limits the preservation of fertility only to males who are able to produce an ejaculate. This fact puts some light on the increase in survival rates of childhood cancer over the past decades because of improvements in the diagnosis and effective treatment in pediatric cancer patients. Therefore, we highlight one of the most important challenges concerning male fertility preservation that is the toxic effect of cancer therapy on reproductive function, especially the spermatogenesis. Currently, the experimental alternative for fertility preservation of prepubertal boys is the testicular tissue cryopreservationfor, for future isolation and spermatogonial stem cells transplantation, in order to restore the spermatogenesis. We present a brief review on isolation, characterization and culture conditions for the in vitro proliferation of spermatogonial stem cells, as well as the future perspectives as an alternative for fertility preservation in prepubertal boys. The possibility of restoring male fertility constitutes a research tool with an huge potential in basic and applied science. The development of these techniques may be a hope for the future of fertility preservation in cases that no other options exist, e.g, pediatric cancer patients.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 42 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 21%
Student > Bachelor 6 14%
Other 4 10%
Student > Ph. D. Student 4 10%
Researcher 3 7%
Other 5 12%
Unknown 11 26%
Readers by discipline Count As %
Medicine and Dentistry 9 21%
Agricultural and Biological Sciences 7 17%
Biochemistry, Genetics and Molecular Biology 5 12%
Immunology and Microbiology 3 7%
Psychology 2 5%
Other 3 7%
Unknown 13 31%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 October 2016.
All research outputs
#4,604,356
of 15,265,759 outputs
Outputs from Einstein (São Paulo)
#35
of 215 outputs
Outputs of similar age
#109,341
of 370,151 outputs
Outputs of similar age from Einstein (São Paulo)
#3
of 9 outputs
Altmetric has tracked 15,265,759 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 215 research outputs from this source. They receive a mean Attention Score of 2.8. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 370,151 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.