↓ Skip to main content

Serum levels of brain-derived neurotrophic factor (BDNF), proBDNF and plasma 3-methoxy-4-hydroxyphenylglycol levels in chronic schizophrenia

Overview of attention for article published in Annals of General Psychiatry, January 2016
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
1 X user
wikipedia
1 Wikipedia page
reddit
1 Redditor

Citations

dimensions_citation
12 Dimensions

Readers on

mendeley
32 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Serum levels of brain-derived neurotrophic factor (BDNF), proBDNF and plasma 3-methoxy-4-hydroxyphenylglycol levels in chronic schizophrenia
Published in
Annals of General Psychiatry, January 2016
DOI 10.1186/s12991-015-0084-9
Pubmed ID
Authors

Reiji Yoshimura, Hikaru Hori, Asuka Katsuki, Kiyokazu Atake, Jun Nakamura

Abstract

We investigated the serum levels of brain-derived neurotrophic factor (BDNF), proBDNF and plasma 3-methoxy-4-hydroxyphenylglycol (MHPG) levels in patients with chronic schizophrenia. Sixty-eight patients who met the DSM-IV-TR criteria and had a chronic schizophrenia (CS) duration of ≥ 5 years were enrolled. Their serum brain-derived BDNF and proBDNF levels were measured by enzyme-linked immunosorbent assays, and their plasma MHPG levels were analyzed by high-performance liquid chromatography with electrochemical detection. The plasma MHPG levels were significantly lower in the CS group (3.9  ±  1.8 ng/ml) compared to those in the group of 32 age- and sex-matched healthy controls (5.1  ±  2.4 ng/ml). The serum BDNF levels were significantly lower in the CS group (8.9  ±  4.8 ng/ml) compared to the control group (12.2.1  ±  6.8 ng/ml). No correlation was observed between plasma MHPG and BDNF in the CS group. These results suggest that hypo-activity of noradrenergic neurons and decreased BDNF secretion exist in chronic schizophrenic patients.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 22%
Student > Ph. D. Student 6 19%
Researcher 5 16%
Student > Doctoral Student 3 9%
Other 2 6%
Other 5 16%
Unknown 4 13%
Readers by discipline Count As %
Neuroscience 9 28%
Medicine and Dentistry 6 19%
Psychology 3 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Nursing and Health Professions 1 3%
Other 3 9%
Unknown 8 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 May 2017.
All research outputs
#8,065,195
of 25,654,806 outputs
Outputs from Annals of General Psychiatry
#197
of 567 outputs
Outputs of similar age
#118,828
of 403,971 outputs
Outputs of similar age from Annals of General Psychiatry
#5
of 10 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 567 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.0. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 403,971 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.