https://t.co/3fpnsyR4z6 "Prostaglandin E2 (PGE2) can increase local blood flow and leukocyte infiltration, enhancing vascular permeability and cytokine production. This bioactive lipid is also involved in CEC-induced spinal inflammation and pain"
https://t.co/3fpnsyR4z6 "A significant increase in cPLA2 activity and AA levels following contusive spinal cord injury at T9 to T10 levels has been reported" "AA-derived prostaglandins and leukotrienes are associated with oxidative damage in the contusiv
https://t.co/3fpnsyR4z6 "AA-containing phosphatidylcholine (PC) is the most preferred substrate of cPLA2, giving rise to lysophosphatidylcholine (LPC) and free AA"
https://t.co/3fpnsyR4z6 "Activation of cytosolic PLA2 (cPLA2) has been shown to produce lipoxidative toxicity, leading to inflammation and pain"