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Acute myocardial infarction, associated with the use of a synthetic adamantyl-cannabinoid: a case report

Overview of attention for article published in BMC Pharmacology and Toxicology, January 2016
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1 tweeter
reddit
1 Redditor

Citations

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28 Dimensions

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39 Mendeley
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Title
Acute myocardial infarction, associated with the use of a synthetic adamantyl-cannabinoid: a case report
Published in
BMC Pharmacology and Toxicology, January 2016
DOI 10.1186/s40360-016-0045-1
Pubmed ID
Authors

Graham McIlroy, Loretta Ford, Jawad M. Khan

Abstract

"Legal highs" are novel psychoactive substances that have evaded statutory control. Synthetic cannabinoid compounds with adamantane moieties have recently been identified, which have high potency at target receptors and are undetectable on conventional toxicology testing. However, little is known about any harmful effects, and their potential to cause serious ill health. We describe a case of myocardial infarction following the use of this class of drug. We report the case of a 39-year-old man admitted after an out-of-hospital cardiac arrest, in whom ECG and elevated cardiac enzymes confirmed ST-elevation myocardial infarction. Normal coronary perfusion was restored after thrombectomy and coronary artery stenting. In the hours preceding his admission, the patient is known to have consumed the legal high product "Black Mamba". Subsequent urine testing confirmed the presence of an adamantyl-group synthetic cannabinoid, whilst cannabis, cocaine, amphetamines and other drugs of abuse were not detected. The use of legal highs is being increasingly recognised, but the chemical compositions and physiological effects of these drugs are poorly characterised and are continually changing. Synthetic cannabinoids, rarely identified on toxicological testing, can be linked to serious adverse cardiovascular events. This case highlights the importance of testing for novel psychoactive compounds, and recognising their potential to cause life-threatening conditions.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 39 100%

Demographic breakdown

Readers by professional status Count As %
Other 10 26%
Student > Bachelor 6 15%
Student > Ph. D. Student 4 10%
Student > Postgraduate 3 8%
Student > Master 3 8%
Other 6 15%
Unknown 7 18%
Readers by discipline Count As %
Medicine and Dentistry 15 38%
Chemistry 4 10%
Psychology 2 5%
Computer Science 2 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Other 6 15%
Unknown 8 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 January 2016.
All research outputs
#10,495,784
of 13,775,877 outputs
Outputs from BMC Pharmacology and Toxicology
#191
of 280 outputs
Outputs of similar age
#207,538
of 334,622 outputs
Outputs of similar age from BMC Pharmacology and Toxicology
#6
of 10 outputs
Altmetric has tracked 13,775,877 research outputs across all sources so far. This one is in the 20th percentile – i.e., 20% of other outputs scored the same or lower than it.
So far Altmetric has tracked 280 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 334,622 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.