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Neuronal mechanisms and circuits underlying repetitive behaviors in mouse models of autism spectrum disorder

Overview of attention for article published in Behavioral and Brain Functions, January 2016
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

Mentioned by

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6 tweeters

Citations

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50 Dimensions

Readers on

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155 Mendeley
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Title
Neuronal mechanisms and circuits underlying repetitive behaviors in mouse models of autism spectrum disorder
Published in
Behavioral and Brain Functions, January 2016
DOI 10.1186/s12993-016-0087-y
Pubmed ID
Authors

Hyopil Kim, Chae-Seok Lim, Bong-Kiun Kaang

Abstract

Autism spectrum disorder (ASD) refers to a broad spectrum of neurodevelopmental disorders characterized by three central behavioral symptoms: impaired social interaction, impaired social communication, and restricted and repetitive behaviors. However, the symptoms are heterogeneous among patients and a number of ASD mouse models have been generated containing mutations that mimic the mutations found in human patients with ASD. Each mouse model was found to display a unique set of repetitive behaviors. In this review, we summarize the repetitive behaviors of the ASD mouse models and variations found in their neural mechanisms including molecular and electrophysiological features. We also propose potential neuronal mechanisms underlying these repetitive behaviors, focusing on the role of the cortico-basal ganglia-thalamic circuits and brain regions associated with both social and repetitive behaviors. Further understanding of molecular and circuitry mechanisms of the repetitive behaviors associated with ASD is necessary to aid the development of effective treatments for these disorders.

Twitter Demographics

The data shown below were collected from the profiles of 6 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 155 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Unknown 154 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 35 23%
Researcher 27 17%
Student > Master 24 15%
Student > Bachelor 18 12%
Student > Postgraduate 7 5%
Other 24 15%
Unknown 20 13%
Readers by discipline Count As %
Neuroscience 54 35%
Agricultural and Biological Sciences 32 21%
Psychology 15 10%
Biochemistry, Genetics and Molecular Biology 7 5%
Medicine and Dentistry 6 4%
Other 16 10%
Unknown 25 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 December 2016.
All research outputs
#4,095,817
of 14,154,038 outputs
Outputs from Behavioral and Brain Functions
#98
of 369 outputs
Outputs of similar age
#94,992
of 336,719 outputs
Outputs of similar age from Behavioral and Brain Functions
#3
of 8 outputs
Altmetric has tracked 14,154,038 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 369 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 336,719 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.