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The Zfx gene is expressed in human gliomas and is important in the proliferation and apoptosis of the human malignant glioma cell line U251

Overview of attention for article published in Journal of Experimental & Clinical Cancer Research, December 2011
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Title
The Zfx gene is expressed in human gliomas and is important in the proliferation and apoptosis of the human malignant glioma cell line U251
Published in
Journal of Experimental & Clinical Cancer Research, December 2011
DOI 10.1186/1756-9966-30-114
Pubmed ID
Authors

Youxin Zhou, Zuopeng Su, Yulun Huang, Ting Sun, Sansong Chen, Tingfeng Wu, Guilin Chen, Xueshun Xie, Bin Li, Ziwei Du

Abstract

Zfx is a zinc finger protein of the Zfy family, whose members are highly conserved in vertebrates. Zfx is a shared transcriptional regulator of both embryonic stem cells (ESC) and hematopoietic stem cells (HSC), which suggests a common genetic basis of self-renewal in embryonic and adult stem cells. The level of Zfx expression correlates with aggressiveness and severity in many cancer types, including prostate cancer, breast cancer, and leukemia. However, the importance of Zfx in human glioma is largely unknown. In the present study, we examined the role of Zfx in human glioma.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Czechia 1 2%
Italy 1 2%
Brazil 1 2%
Unknown 39 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 21%
Student > Ph. D. Student 6 14%
Student > Doctoral Student 4 10%
Student > Bachelor 4 10%
Professor > Associate Professor 4 10%
Other 8 19%
Unknown 7 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 29%
Biochemistry, Genetics and Molecular Biology 10 24%
Medicine and Dentistry 7 17%
Linguistics 1 2%
Neuroscience 1 2%
Other 1 2%
Unknown 10 24%