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A study of the antioxidant effect of alpha lipoic acids on sperm quality

Overview of attention for article published in Clinics, January 2008
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (59th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

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2 tweeters

Citations

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59 Dimensions

Readers on

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52 Mendeley
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Title
A study of the antioxidant effect of alpha lipoic acids on sperm quality
Published in
Clinics, January 2008
DOI 10.1590/s1807-59322008000400022
Pubmed ID
Authors

Siti Fatimah Ibrahim, Khairul Osman, Srijit Das, Abas Mazni Othman, Norzaiti Abdul Majid, Mohd Padzil Abdul Rahman

Abstract

Assisted reproductive techniques are useful in helping infertile couples achieve successful conception. Initial studies have shown that sperm cryopreservation, one step in assisted reproduction, causes a dramatic reduction in sperm quality. This has been attributed to, among other things, free radical activities. The aim of the present study was to minimize this oxidative attack by adding an antioxidant into the sperm microenvironment. Alpha lipoic acids were selected for this purpose for their efficient free radical scavenging properties and solubility in lipid and aqueous phases. For this investigation, semen from six Boer bucks was pooled. Seminal analysis of the baseline prior to incubation of samples with different concentrations of Alpha lipoic acids (0.00625, 0.0125, 0.025, 0.05, 0.1 mmol/ml) was performed, and post-seminal analysis was conducted after a one-hour incubation. The comet assay was used to observe the effect of Alpha lipoic acids on sperm DNA integrity. Statistical analysis using an unpaired t-test with a significance level of p<0.05 was then performed. Our results indicate that the sperm motility rate was improved after incubation with Alpha lipoic acids at a concentration of 0.02 mmol/ml. This concentration was also capable of reducing DNA damage. In conclusion, Alpha lipoic acids renders cryoprotection to sperm, thereby improving sperm quality.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Iran, Islamic Republic of 1 2%
Brazil 1 2%
Unknown 50 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 19%
Student > Bachelor 8 15%
Researcher 7 13%
Professor > Associate Professor 5 10%
Student > Master 4 8%
Other 9 17%
Unknown 9 17%
Readers by discipline Count As %
Medicine and Dentistry 12 23%
Agricultural and Biological Sciences 11 21%
Veterinary Science and Veterinary Medicine 4 8%
Pharmacology, Toxicology and Pharmaceutical Science 4 8%
Biochemistry, Genetics and Molecular Biology 2 4%
Other 4 8%
Unknown 15 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 February 2017.
All research outputs
#3,992,222
of 9,031,633 outputs
Outputs from Clinics
#133
of 312 outputs
Outputs of similar age
#131,244
of 339,386 outputs
Outputs of similar age from Clinics
#1
of 5 outputs
Altmetric has tracked 9,031,633 research outputs across all sources so far. This one has received more attention than most of these and is in the 54th percentile.
So far Altmetric has tracked 312 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 339,386 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them