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Pluripotent stem cells in disease modelling and drug discovery

Overview of attention for article published in Nature Reviews Molecular Cell Biology, January 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

news
2 news outlets
twitter
33 X users
patent
1 patent
facebook
16 Facebook pages
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
489 Dimensions

Readers on

mendeley
1204 Mendeley
citeulike
3 CiteULike
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Title
Pluripotent stem cells in disease modelling and drug discovery
Published in
Nature Reviews Molecular Cell Biology, January 2016
DOI 10.1038/nrm.2015.27
Pubmed ID
Authors

Yishai Avior, Ido Sagi, Nissim Benvenisty

Abstract

Experimental modelling of human disorders enables the definition of the cellular and molecular mechanisms underlying diseases and the development of therapies for treating them. The availability of human pluripotent stem cells (PSCs), which are capable of self-renewal and have the potential to differentiate into virtually any cell type, can now help to overcome the limitations of animal models for certain disorders. The ability to model human diseases using cultured PSCs has revolutionized the ways in which we study monogenic, complex and epigenetic disorders, as well as early- and late-onset diseases. Several strategies are used to generate such disease models using either embryonic stem cells (ES cells) or patient-specific induced PSCs (iPSCs), creating new possibilities for the establishment of models and their use in drug screening.

X Demographics

X Demographics

The data shown below were collected from the profiles of 33 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 1,204 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 <1%
Brazil 2 <1%
Germany 2 <1%
Denmark 2 <1%
Korea, Republic of 1 <1%
India 1 <1%
United Kingdom 1 <1%
Taiwan 1 <1%
Colombia 1 <1%
Other 4 <1%
Unknown 1185 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 262 22%
Researcher 182 15%
Student > Bachelor 174 14%
Student > Master 149 12%
Student > Postgraduate 62 5%
Other 163 14%
Unknown 212 18%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 350 29%
Agricultural and Biological Sciences 269 22%
Neuroscience 103 9%
Medicine and Dentistry 84 7%
Engineering 50 4%
Other 113 9%
Unknown 235 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 45. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 December 2022.
All research outputs
#943,746
of 25,837,817 outputs
Outputs from Nature Reviews Molecular Cell Biology
#229
of 2,651 outputs
Outputs of similar age
#16,791
of 409,103 outputs
Outputs of similar age from Nature Reviews Molecular Cell Biology
#6
of 42 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,651 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.4. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 409,103 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.