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Prevalence and clinical impact of magnesium disorders in end-stage renal disease: a protocol for a systematic review

Overview of attention for article published in Systematic Reviews, May 2015
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Mentioned by

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1 tweeter
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1 Facebook page

Citations

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2 Dimensions

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24 Mendeley
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Title
Prevalence and clinical impact of magnesium disorders in end-stage renal disease: a protocol for a systematic review
Published in
Systematic Reviews, May 2015
DOI 10.1186/s13643-015-0063-x
Pubmed ID
Authors

John Floridis, Asanga Abeyaratne, Sandawana William Majoni

Abstract

Magnesium plays a key role in maintaining internal homeostasis through actions in the musculoskeletal, nervous, endocrine and cellular messenger systems. Renal excretion is the major route of magnesium elimination from the body. A positive magnesium balance would be expected in renal failure. However, a compensatory decrease in tubular reabsorption is expected to operate to maintain adequate urinary magnesium excretion even when glomerular filtration rate is very low. Patients with end-stage renal disease and those on dialysis have impaired regulatory mechanisms, predisposing them to disturbances in magnesium levels. The effects of high or low magnesium can have deleterious health outcomes, which impact on the co-morbidities and outcomes of chronic renal disease. This systematic review aims to determine the prevalence and clinical outcomes of magnesium disorders in end-stage renal disease. We will undertake a comprehensive search of various databases, MEDLINE, PubMED, EMBASE, Cochrane Library, Cochrane Collaboration, CIHNAL (Ebsco), Web of Science and Google Scholar, for observational studies and clinical trials on magnesium disorders in end-stage renal disease using key terms to identify papers for inclusion. Paper selection and data extraction (where appropriate) will be performed in duplicate on socio-demographic characteristics of participants, diagnosis of end-stage renal disease, magnesium levels, prevalence and clinical outcomes. An assessment of quality will be performed using a modified Newcastle-Ottawa Scale (NOS), including identification of any bias, which may influence findings. Data will be pooled together according to whether the studies were on pre-dialysis, hemodialysis or peritoneal dialysis participants. References from individual papers will also be screened as appropriate. Paper organisation and data extraction and analysis will take place using Microsoft Excel® and Stata version 13®. This systematic review will represent a significant effort at pooling together information on prevalence and outcomes of magnesium disturbances amongst end-stage renal disease patients, which may guide further research and management of the disorders. PROSPERO: CRD42014014354.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 4%
Unknown 23 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 21%
Student > Postgraduate 4 17%
Student > Ph. D. Student 4 17%
Student > Doctoral Student 2 8%
Librarian 2 8%
Other 5 21%
Unknown 2 8%
Readers by discipline Count As %
Medicine and Dentistry 11 46%
Nursing and Health Professions 4 17%
Social Sciences 2 8%
Agricultural and Biological Sciences 1 4%
Computer Science 1 4%
Other 3 13%
Unknown 2 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 February 2016.
All research outputs
#3,432,934
of 7,211,484 outputs
Outputs from Systematic Reviews
#399
of 554 outputs
Outputs of similar age
#154,416
of 320,812 outputs
Outputs of similar age from Systematic Reviews
#32
of 46 outputs
Altmetric has tracked 7,211,484 research outputs across all sources so far. This one is in the 49th percentile – i.e., 49% of other outputs scored the same or lower than it.
So far Altmetric has tracked 554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,812 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 46 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.