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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Blood-brain Barrier Remodeling during Brain Metastasis Formation
|
|---|---|
| Published in |
Molecular Medicine, January 2016
|
| DOI | 10.2119/molmed.2015.00207 |
| Pubmed ID | |
| Authors |
Jagoda K Wrobel, Michal Toborek |
| Abstract |
Our understanding of the process of metastatic progression has improved markedly over the past decades, yet metastasis remains the most enigmatic component of cancer pathogenesis. This lack of knowledge has serious health-related implications, as metastasis is responsible for 90% of all cancer-related mortalities. The brain is considered a sanctuary site for metastatic tumor growth, where the blood-brain barrier and other components of the brain microenvironment, provide protection to the tumor cells from immune surveillance, chemotherapeutics and other potentially harmful substances. The interactions between tumor cells and the brain microenvironment, principally brain vascular endothelium, are the critical determinants in their progression towards metastasis, dormancy, or clearance. This review discusses current knowledge of the biology of metastatic progression, with a particular focus on the tumor cell migration and colonization in the brain. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 105 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 25 | 24% |
| Researcher | 16 | 15% |
| Student > Bachelor | 16 | 15% |
| Student > Master | 8 | 8% |
| Student > Doctoral Student | 7 | 7% |
| Other | 13 | 12% |
| Unknown | 20 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 25 | 24% |
| Medicine and Dentistry | 16 | 15% |
| Agricultural and Biological Sciences | 10 | 10% |
| Engineering | 6 | 6% |
| Neuroscience | 5 | 5% |
| Other | 14 | 13% |
| Unknown | 29 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2016.
All research outputs
#15,355,821
of 22,842,950 outputs
Outputs from Molecular Medicine
#808
of 1,139 outputs
Outputs of similar age
#231,938
of 395,522 outputs
Outputs of similar age from Molecular Medicine
#7
of 15 outputs
Altmetric has tracked 22,842,950 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,139 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 395,522 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.