Analysis and correction of compositional bias in sparse sequencing count data

First up, Senthil Muthiah on estimating absolute concentrations of taxa from relative abundance mgx data. https://t.co/zqhfkQJJM5 #SACMDA3

RT @jamietmorton: @JTNearing @MehrbodEstaki I also like ALDEx2, but the hypothesis test is not too hard to break -- if your mean environmen…

@JTNearing @MehrbodEstaki I also like ALDEx2, but the hypothesis test is not too hard to break -- if your mean environment absolute abundance is actually changing, you are toast. Checkout this paper if you haven't already: https://t.co/1kwVlEjQWb

When reviewers point out that formal statistical methodologies for #RNAseq work better, but .. (I am reference [58]) https://t.co/Llh3lwcSFR One response: first we take Manhattan (small RNAseq) then we take Berlin (solveco mputational issues before applyi