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Phase separation in biology; functional organization of a higher order

Overview of attention for article published in Cell Communication and Signaling, January 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#23 of 1,139)
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

news
2 news outlets
twitter
7 X users
patent
1 patent
facebook
1 Facebook page

Citations

dimensions_citation
567 Dimensions

Readers on

mendeley
423 Mendeley
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Title
Phase separation in biology; functional organization of a higher order
Published in
Cell Communication and Signaling, January 2016
DOI 10.1186/s12964-015-0125-7
Pubmed ID
Authors

Diana M. Mitrea, Richard W. Kriwacki

Abstract

Inside eukaryotic cells, macromolecules are partitioned into membrane-bounded compartments and, within these, some are further organized into non-membrane-bounded structures termed membrane-less organelles. The latter structures are comprised of heterogeneous mixtures of proteins and nucleic acids and assemble through a phase separation phenomenon similar to polymer condensation. Membrane-less organelles are dynamic structures maintained through multivalent interactions that mediate diverse biological processes, many involved in RNA metabolism. They rapidly exchange components with the cellular milieu and their properties are readily altered in response to environmental cues, often implicating membrane-less organelles in responses to stress signaling. In this review, we discuss: (1) the functional roles of membrane-less organelles, (2) unifying structural and mechanistic principles that underlie their assembly and disassembly, and (3) established and emerging methods used in structural investigations of membrane-less organelles.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 423 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 423 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 104 25%
Researcher 60 14%
Student > Bachelor 47 11%
Student > Master 46 11%
Student > Doctoral Student 21 5%
Other 46 11%
Unknown 99 23%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 168 40%
Agricultural and Biological Sciences 47 11%
Chemistry 39 9%
Physics and Astronomy 12 3%
Engineering 11 3%
Other 43 10%
Unknown 103 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 June 2023.
All research outputs
#1,454,828
of 23,928,031 outputs
Outputs from Cell Communication and Signaling
#23
of 1,139 outputs
Outputs of similar age
#26,209
of 400,296 outputs
Outputs of similar age from Cell Communication and Signaling
#2
of 7 outputs
Altmetric has tracked 23,928,031 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,139 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 400,296 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.