Title |
Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways
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Published in |
Breast Cancer Research, March 2010
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DOI | 10.1186/bcr2560 |
Pubmed ID | |
Authors |
Elgene Lim, Di Wu, Bhupinder Pal, Toula Bouras, Marie-Liesse Asselin-Labat, François Vaillant, Hideo Yagita, Geoffrey J Lindeman, Gordon K Smyth, Jane E Visvader |
Abstract |
Molecular characterization of the normal epithelial cell types that reside in the mammary gland is an important step toward understanding pathways that regulate self-renewal, lineage commitment, and differentiation along the hierarchy. Here we determined the gene expression signatures of four distinct subpopulations isolated from the mouse mammary gland. The epithelial cell signatures were used to interrogate mouse models of mammary tumorigenesis and to compare with their normal human counterpart subsets to identify conserved genes and networks. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 4 | 1% |
Canada | 2 | <1% |
Australia | 1 | <1% |
Sweden | 1 | <1% |
Italy | 1 | <1% |
Germany | 1 | <1% |
Singapore | 1 | <1% |
Iran, Islamic Republic of | 1 | <1% |
United States | 1 | <1% |
Other | 0 | 0% |
Unknown | 287 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 76 | 25% |
Researcher | 71 | 24% |
Student > Master | 32 | 11% |
Student > Doctoral Student | 18 | 6% |
Professor > Associate Professor | 17 | 6% |
Other | 40 | 13% |
Unknown | 46 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 115 | 38% |
Biochemistry, Genetics and Molecular Biology | 69 | 23% |
Medicine and Dentistry | 29 | 10% |
Immunology and Microbiology | 7 | 2% |
Mathematics | 5 | 2% |
Other | 24 | 8% |
Unknown | 51 | 17% |