Androgen Receptor Agonist Active in Resistant ER+ Breast Cancer
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Meeting Coverage > MBCC Also: Combination targets uncommon form of advanced HER2-mutant disease by Charles Bankhead, Senior…
Meeting Coverage > MBCC Also: Combination targets uncommon form of advanced HER2-mutant disease by Charles Bankhead, Senior…
Crystal structure of a portion of the HER2 protein. Credit: RCSB PDB Metastatic breast cancers treated with hormone therapy can…
大约七成乳腺癌的雌激素受体为阳性,其主要治疗手段为雌激素受体靶向药物。不过,几乎所有的雌激素受体阳性乳腺癌发生转移后,对雌激素受体靶向疗法产生耐药。除了已知25%~30%的芳香酶抑制剂治疗患者雌激素受体编码基因ESR1 2018年12月10日,英国《自然》旗…