Bh3 profiling could predict in real time which drug/combo drug will likely benefit the patient without knowing the genetics (last 2 links) Study explains why many #cancer drugs fail during #clinicaltrials https://t.co/cEfPoIV1sd https://t.co/pFZdDBVKpp
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To get around this, we developed a technology that makes sensitive single cell measurements of apoptotic priming using BH3 profiling (https://t.co/Igy6Chmu0L), and multiplexed immunofluorescence using CyCIF (https://t.co/rSzgTSCPDD) on the same single cell
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Discover two in vitro flow cytometry-based methods useful for measuring #BCL-2proteins and mitochondrial-based cell death in complex cell populations in Methods in Molecular Biology developed by Dr James LaBelle: https://t.co/Xe8K10aq0n https://t.co/i0j11z
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Great innovation: high throughput FLIM-FRET #microscopy in 384 well format to study protein interactions by a great collaborator @Sunnybrook https://t.co/c2UmLFT5bL