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Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases

Overview of attention for book
Attention for Chapter 5: Brain Food for Alzheimer-Free Ageing: Focus on Herbal Medicines
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#39 of 3,348)
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

news
5 news outlets
twitter
9 tweeters
facebook
6 Facebook pages
googleplus
1 Google+ user
reddit
1 Redditor
video
2 video uploaders

Citations

dimensions_citation
9 Dimensions

Readers on

mendeley
43 Mendeley
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Chapter title
Brain Food for Alzheimer-Free Ageing: Focus on Herbal Medicines
Chapter number 5
Book title
Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases
Published in
Advances in experimental medicine and biology, January 2015
DOI 10.1007/978-3-319-18365-7_5
Pubmed ID
Book ISBNs
978-3-31-918364-0, 978-3-31-918365-7
Authors

Hügel, Helmut M, Helmut M Hügel, Helmut M. Hügel, Hügel, Helmut M.

Editors

Neville Vassallo

Abstract

Healthy brain aging and the problems of dementia and Alzheimer's disease (AD) are a global concern. Beyond 60 years of age, most, if not everyone, will experience a decline in cognitive skills, memory capacity and changes in brain structure. Longevity eventually leads to an accumulation of amyloid plaques and/or tau tangles, including some vascular dementia damage. Therefore, lifestyle choices are paramount to leading either a brain-derived or a brain-deprived life. The focus of this review is to critically examine the evidence, impact, influence and mechanisms of natural products as chemopreventive agents which induce therapeutic outcomes that modulate the aggregation process of beta-amyloid (Aβ), providing measureable cognitive benefits in the aging process. Plants can be considered as chemical factories that manufacture huge numbers of diverse bioactive substances, many of which have the potential to provide substantial neuroprotective benefits. Medicinal herbs and health food supplements have been widely used in Asia since over 2,000 years. The phytochemicals utilized in traditional Chinese medicine have demonstrated safety profiles for human consumption. Many herbs with anti-amyloidogenic activity, including those containing polyphenolic constituents such as green tea, turmeric, Salvia miltiorrhiza, and Panax ginseng, are presented. Also covered in this review are extracts from kitchen spices including cinnamon, ginger, rosemary, sage, salvia herbs, Chinese celery and many others some of which are commonly used in herbal combinations and represent highly promising therapeutic natural compounds against AD. A number of clinical trials conducted on herbs to counter dementia and AD are discussed.

Twitter Demographics

The data shown below were collected from the profiles of 9 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 42 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 16%
Researcher 5 12%
Student > Ph. D. Student 5 12%
Student > Bachelor 5 12%
Student > Doctoral Student 5 12%
Other 9 21%
Unknown 7 16%
Readers by discipline Count As %
Medicine and Dentistry 8 19%
Agricultural and Biological Sciences 7 16%
Neuroscience 5 12%
Nursing and Health Professions 3 7%
Chemistry 2 5%
Other 8 19%
Unknown 10 23%

Attention Score in Context

This research output has an Altmetric Attention Score of 46. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 January 2020.
All research outputs
#416,102
of 14,308,949 outputs
Outputs from Advances in experimental medicine and biology
#39
of 3,348 outputs
Outputs of similar age
#8,113
of 233,307 outputs
Outputs of similar age from Advances in experimental medicine and biology
#2
of 30 outputs
Altmetric has tracked 14,308,949 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,348 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 233,307 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.