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Glioma Signaling

Overview of attention for book
Attention for Chapter 11: Cannabinoid signaling in glioma cells.
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

twitter
10 tweeters
facebook
50 Facebook pages
googleplus
3 Google+ users

Citations

dimensions_citation
10 Dimensions

Readers on

mendeley
30 Mendeley
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Chapter title
Cannabinoid signaling in glioma cells.
Chapter number 11
Book title
Glioma Signaling
Published in
Advances in experimental medicine and biology, July 2012
DOI 10.1007/978-94-007-4719-7_11
Pubmed ID
Book ISBNs
978-9-40-074718-0, 978-9-40-074719-7
Authors

Aleksandra Ellert-Miklaszewska, Iwona Ciechomska, Bozena Kaminska

Editors

Jolanta Barańska

Abstract

Cannabinoids are a group of structurally heterogeneous but pharmacologically related compounds, including plant-derived cannabinoids, synthetic substances and endogenous cannabinoids, such as anandamide and 2-arachidonoylglycerol. Cannabinoids elicit a wide range of central and peripheral effects mostly mediated through cannabinoid receptors. There are two types of specific G(i/o)-protein-coupled receptors cloned so far, called CB1 and CB2, although an existence of additional cannabinoid-binding receptors has been suggested. CB1 and CB2 differ in their predicted amino acid sequence, tissue distribution, physiological role and signaling mechanisms. Significant alterations of a balance in the cannabinoid system between the levels of endogenous ligands and their receptors occur during malignant transformation in various types of cancer, including gliomas. Cannabinoids exert anti-proliferative action in tumor cells. Induction of cell death by cannabinoid treatment relies on the generation of a pro-apoptotic sphingolipid ceramide and disruption of signaling pathways crucial for regulation of cellular proliferation, differentiation or apoptosis. Increased ceramide levels lead also to ER-stress and autophagy in drug-treated glioblastoma cells.

Twitter Demographics

The data shown below were collected from the profiles of 10 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Denmark 1 3%
Unknown 28 93%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 17%
Researcher 4 13%
Student > Doctoral Student 3 10%
Professor 3 10%
Student > Master 3 10%
Other 6 20%
Unknown 6 20%
Readers by discipline Count As %
Medicine and Dentistry 6 20%
Agricultural and Biological Sciences 4 13%
Biochemistry, Genetics and Molecular Biology 3 10%
Neuroscience 3 10%
Immunology and Microbiology 1 3%
Other 5 17%
Unknown 8 27%

Attention Score in Context

This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 July 2019.
All research outputs
#998,151
of 17,367,552 outputs
Outputs from Advances in experimental medicine and biology
#112
of 3,926 outputs
Outputs of similar age
#6,628
of 135,513 outputs
Outputs of similar age from Advances in experimental medicine and biology
#2
of 21 outputs
Altmetric has tracked 17,367,552 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,926 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 135,513 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.