James Pickett @JamesPickett12 @alzheimerssoc, noted the @MathiasJucker study https://t.co/mTe7cLlso8 had limitations, including that it only looked at those who had a genetic predisposition to Alzheimer’s – which only affects 1% of those with the condition
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Very cool @MathiasJucker love a reprint!
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@MikeNGladstone @SaraNayeem Similar to previous DIAN study. DIAN study looked at APP/PSEN1/PSEN2 while here everyone has PSEN1. The DIAN study showed sig serum NfL at 16.2 yrs vs 22. Both very relatable. Very reminiscent of Dr. Nancy Wexler's work in Barr
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Link to Preische et al (NMED 2019) as well https://t.co/c3ZmLECdwd