Acarbose is superior to metformin on both efficacy (lifespan extension) and tox (acarbose is not absorbed into the bloodstream like metformin). https://t.co/aFBj39qENd
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@MaxUnfried Acarbose also reduces 'carbotoxicity' but it's not a systemic agent like metformin: https://t.co/aFBj39qENd
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@AlexanderMWolf7 @AdamsBioAging @BradStanfieldMD Some evidence from Acarbose and Canagliflozin in the ITP https://t.co/vYHiOULDIQ https://t.co/dkG3O4M4Bw
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@Boldizar @mkaeberlein @BittoAlessandro https://t.co/hLXvHLmIEQ look at the survival times in the references. They’re not promising when you average them out. In one, controls outlive aca by 14%. Most showed no increase in survival, even in the males.