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Whole genome sequence analysis of BT-474 using complete Genomics’ standard and long fragment read technologies

Overview of attention for article published in Giga Science, February 2016
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (67th percentile)

Mentioned by

twitter
4 tweeters
peer_reviews
1 peer review site
facebook
1 Facebook page

Citations

dimensions_citation
2 Dimensions

Readers on

mendeley
16 Mendeley
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Title
Whole genome sequence analysis of BT-474 using complete Genomics’ standard and long fragment read technologies
Published in
Giga Science, February 2016
DOI 10.1186/s13742-016-0113-x
Pubmed ID
Authors

Serban Ciotlos, Qing Mao, Rebecca Yu Zhang, Zhenyu Li, Robert Chin, Natali Gulbahce, Sophie Jia Liu, Radoje Drmanac, Brock A. Peters

Abstract

The cell line BT-474 is a popular cell line for studying the biology of cancer and developing novel drugs. However, there is no complete, published genome sequence for this highly utilized scientific resource. In this study we sought to provide a comprehensive and useful data set for the scientific community by generating a whole genome sequence for BT-474. Five μg of genomic DNA, isolated from an early passage of the BT-474 cell line, was used to generate a whole genome sequence (114X coverage) using Complete Genomics' standard sequencing process. To provide additional variant phasing and structural variation data we also processed and analyzed two separate libraries of 5 and 6 individual cells to depths of 99X and 87X, respectively, using Complete Genomics' Long Fragment Read (LFR) technology. BT-474 is a highly aneuploid cell line with an extremely complex genome sequence. This ~300X total coverage genome sequence provides a more complete understanding of this highly utilized cell line at the genomic level.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 50%
Researcher 2 13%
Unspecified 1 6%
Professor 1 6%
Student > Master 1 6%
Other 2 13%
Unknown 1 6%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 9 56%
Agricultural and Biological Sciences 3 19%
Computer Science 1 6%
Unspecified 1 6%
Immunology and Microbiology 1 6%
Other 0 0%
Unknown 1 6%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 February 2016.
All research outputs
#2,029,837
of 8,073,039 outputs
Outputs from Giga Science
#235
of 256 outputs
Outputs of similar age
#100,475
of 332,083 outputs
Outputs of similar age from Giga Science
#15
of 16 outputs
Altmetric has tracked 8,073,039 research outputs across all sources so far. This one has received more attention than most of these and is in the 61st percentile.
So far Altmetric has tracked 256 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.2. This one is in the 7th percentile – i.e., 7% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 332,083 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.