Immune dysfunction as a precursor to neurodegeneration is revealed partly through GWAS. It's remarkable that interleukin is implicated in delirium GWAS for example. There is a molecular basis to some aspects of delirium. https://t.co/7PVq9elIwD
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Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. New locus at chromosome 7q36 within the DPP6 gene led by rs118113626. htt
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A study based on the largest cohort of unrelated FTLD-TDP patients to date provides a comprehensive view of the genetic landscape of FTLD-TDP, nominates novel FTLD-TDP risk loci and strongly implicates the immune pathway in FTLD-TDP pathogenesis: https://t
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RT @Neuro_Genomics: In another collaborative effort, and using whole genome sequencing data we identified additional novel risk genes for…