Title |
Recent progress in the study of brown adipose tissue
|
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Published in |
Cell & Bioscience, October 2011
|
DOI | 10.1186/2045-3701-1-35 |
Pubmed ID | |
Authors |
Xuan Yao, Shifang Shan, Ying Zhang, Hao Ying |
Abstract |
Brown adipose tissue in mammals plays a critical role in maintaining energy balance by thermogenesis, which means dissipating energy in the form of heat. It is held that in mammals, long-term surplus food intake results in energy storage in the form of triglyceride and may eventually lead to obesity. Stimulating energy-dissipating function of brown adipose tissue in human body may counteract fat accumulation. In order to utilize brown adipose tissue as a therapeutic target, the mechanisms underlying brown adipocyte differentiation and function should be better elucidated. Here we review the molecular mechanisms involved in brown adipose tissue development and thermogenesis, and share our thoughts on current challenges and possible future therapeutic approaches. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 2% |
Spain | 2 | 2% |
Portugal | 1 | <1% |
United Kingdom | 1 | <1% |
Ireland | 1 | <1% |
Brazil | 1 | <1% |
China | 1 | <1% |
Unknown | 92 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 29 | 29% |
Researcher | 16 | 16% |
Student > Master | 16 | 16% |
Student > Bachelor | 11 | 11% |
Student > Doctoral Student | 5 | 5% |
Other | 16 | 16% |
Unknown | 8 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 50 | 50% |
Medicine and Dentistry | 16 | 16% |
Biochemistry, Genetics and Molecular Biology | 9 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
Neuroscience | 3 | 3% |
Other | 8 | 8% |
Unknown | 12 | 12% |