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Resveratrol Engages AMPK to Attenuate ERK and mTOR Signaling in Sensory Neurons and Inhibits Incision-Induced Acute and Chronic Pain

Overview of attention for article published in Molecular Pain, January 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

twitter
4 tweeters
patent
1 patent
facebook
2 Facebook pages

Citations

dimensions_citation
132 Dimensions

Readers on

mendeley
110 Mendeley

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Title
Resveratrol Engages AMPK to Attenuate ERK and mTOR Signaling in Sensory Neurons and Inhibits Incision-Induced Acute and Chronic Pain
Published in
Molecular Pain, January 2012
DOI 10.1186/1744-8069-8-5
Pubmed ID
22269797
Authors

Dipti V Tillu, Ohannes K Melemedjian, Marina N Asiedu, Ning Qu, Milena De Felice, Gregory Dussor, Theodore J Price

Abstract

Despite advances in our understanding of basic mechanisms driving post-surgical pain, treating incision-induced pain remains a major clinical challenge. Moreover, surgery has been implicated as a major cause of chronic pain conditions. Hence, more efficacious treatments are needed to inhibit incision-induced pain and prevent the transition to chronic pain following surgery. We reasoned that activators of AMP-activated protein kinase (AMPK) may represent a novel treatment avenue for the local treatment of incision-induced pain because AMPK activators inhibit ERK and mTOR signaling, two important pathways involved in the sensitization of peripheral nociceptors.

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Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Turkey 1 <1%
France 1 <1%
Czechia 1 <1%
United Kingdom 1 <1%
Russia 1 <1%
United States 1 <1%
Unknown 104 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 22 20%
Student > Ph. D. Student 20 18%
Student > Master 18 16%
Student > Doctoral Student 10 9%
Student > Bachelor 9 8%
Other 20 18%
Unknown 11 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 34 31%
Medicine and Dentistry 20 18%
Neuroscience 15 14%
Biochemistry, Genetics and Molecular Biology 13 12%
Pharmacology, Toxicology and Pharmaceutical Science 6 5%
Other 5 5%
Unknown 17 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 September 2021.
All research outputs
#3,526,442
of 20,380,948 outputs
Outputs from Molecular Pain
#57
of 592 outputs
Outputs of similar age
#35,799
of 242,089 outputs
Outputs of similar age from Molecular Pain
#9
of 47 outputs
Altmetric has tracked 20,380,948 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 592 research outputs from this source. They receive a mean Attention Score of 4.2. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,089 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.

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