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Resveratrol Engages AMPK to Attenuate ERK and mTOR Signaling in Sensory Neurons and Inhibits Incision-Induced Acute and Chronic Pain

Overview of attention for article published in Molecular Pain, January 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

Mentioned by

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4 X users
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1 patent
facebook
2 Facebook pages

Citations

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150 Dimensions

Readers on

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122 Mendeley
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Title
Resveratrol Engages AMPK to Attenuate ERK and mTOR Signaling in Sensory Neurons and Inhibits Incision-Induced Acute and Chronic Pain
Published in
Molecular Pain, January 2012
DOI 10.1186/1744-8069-8-5
Pubmed ID
Authors

Dipti V Tillu, Ohannes K Melemedjian, Marina N Asiedu, Ning Qu, Milena De Felice, Gregory Dussor, Theodore J Price

Abstract

Despite advances in our understanding of basic mechanisms driving post-surgical pain, treating incision-induced pain remains a major clinical challenge. Moreover, surgery has been implicated as a major cause of chronic pain conditions. Hence, more efficacious treatments are needed to inhibit incision-induced pain and prevent the transition to chronic pain following surgery. We reasoned that activators of AMP-activated protein kinase (AMPK) may represent a novel treatment avenue for the local treatment of incision-induced pain because AMPK activators inhibit ERK and mTOR signaling, two important pathways involved in the sensitization of peripheral nociceptors.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 122 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Turkey 1 <1%
France 1 <1%
Czechia 1 <1%
United Kingdom 1 <1%
Russia 1 <1%
United States 1 <1%
Unknown 116 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 22 18%
Student > Ph. D. Student 20 16%
Student > Master 20 16%
Student > Doctoral Student 10 8%
Student > Bachelor 10 8%
Other 22 18%
Unknown 18 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 34 28%
Medicine and Dentistry 24 20%
Neuroscience 15 12%
Biochemistry, Genetics and Molecular Biology 12 10%
Pharmacology, Toxicology and Pharmaceutical Science 6 5%
Other 7 6%
Unknown 24 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 September 2021.
All research outputs
#4,659,159
of 25,373,627 outputs
Outputs from Molecular Pain
#83
of 669 outputs
Outputs of similar age
#36,498
of 250,087 outputs
Outputs of similar age from Molecular Pain
#11
of 47 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 250,087 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.