👓️👓️ If β-amyloid is helping protect AD patients from chronic and potentially lethal neuroinfection, then amyloidosis is playing a beneficial immune role in late life and Aβ fibrillization activities do not satisfy classical criteria for antagonistic pleio
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老化における低進化的淘汰圧は 脊椎動物ゲノムにおけるAβ持続性を説明しないhttps://t.co/GOyUA0zxS5 Aβは脊椎動物全体で発現する古代神経ペプチド 少なくとも4億年 人間と異なり、脊椎動物の殆どは老化で繁殖停止せず、淘汰圧は老年期まで維持 ⇨老化での低選択圧は、全脊椎動物Aβ持続性説明不能
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Low Evolutionary Selection Pressure in Senescence Does Not Explain the Persistence of Aβ in the Vertebrate Genome. https://t.co/Cj5eqBBpQj
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Low Evolutionary Selection Pressure in Senescence Does Not Explain the Persistence of Aβ in the Vertebrate Genome https://t.co/YYaNicC8M4 https://t.co/WZ9cfFu1es