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The Neuropharmacology of Alcohol

Overview of attention for book
Cover of 'The Neuropharmacology of Alcohol'

Table of Contents

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    Book Overview
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    Chapter 76 Presynaptic Ethanol Actions: Potential Roles in Ethanol Seeking
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    Chapter 77 Ethanol and Cytokines in the Central Nervous System
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    Chapter 78 Voltage-Sensitive Potassium Channels of the BK Type and Their Coding Genes Are Alcohol Targets in Neurons
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    Chapter 79 Advances in Pharmacotherapy Development: Human Clinical Studies
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    Chapter 80 GABA A Receptor Subtype Mechanisms and the Abuse-Related Effects of Ethanol: Genetic and Pharmacological Evidence
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    Chapter 82 Dynamic Adaptation in Neurosteroid Networks in Response to Alcohol
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    Chapter 85 Advancing Pharmacotherapy Development from Preclinical Animal Studies
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    Chapter 86 Corticotropin-Releasing Factor (CRF) Neurocircuitry and Neuropharmacology in Alcohol Drinking
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    Chapter 88 Hepatic Immune System: Adaptations to Alcohol
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    Chapter 89 Molecular, Neuronal, and Behavioral Effects of Ethanol and Nicotine Interactions
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    Chapter 90 Chronic Alcohol, Intrinsic Excitability, and Potassium Channels: Neuroadaptations and Drinking Behavior
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    Chapter 92 Innate Immune Signaling and Alcohol Use Disorders
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    Chapter 93 Voltage-Sensitive Calcium Channels in the Brain: Relevance to Alcohol Intoxication and Withdrawal
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    Chapter 98 GABA and Glutamate Synaptic Coadaptations to Chronic Ethanol in the Striatum
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    Chapter 100 Contribution of Dynorphin and Orexin Neuropeptide Systems to the Motivational Effects of Alcohol
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    Chapter 101 Transcriptional Regulators as Targets for Alcohol Pharmacotherapies
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    Chapter 105 Do Alcohol-Related AMPA-Type Glutamate Receptor Adaptations Promote Intake?
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    Chapter 106 Cross-Species Alterations in Synaptic Dopamine Regulation After Chronic Alcohol Exposure
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    Chapter 108 Central Noradrenergic Interactions with Alcohol and Regulation of Alcohol-Related Behaviors
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    Chapter 109 The Cerebellar GABA A R System as a Potential Target for Treating Alcohol Use Disorder
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    Chapter 189 Correction to: Presynaptic Ethanol Actions: Potential Roles in Ethanol Seeking
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    Chapter 190 Correction to: GABA A Receptor Subtype Mechanisms and the Abuse-Related Effects of Ethanol: Genetic and Pharmacological Evidence
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    Chapter 191 Correction to: Advancing Pharmacotherapy Development from Preclinical Animal Studies
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    Chapter 192 Correction to: Chronic Alcohol, Intrinsic Excitability, and Potassium Channels: Neuroadaptations and Drinking Behavior
  26. Altmetric Badge
    Chapter 193 Correction to: Innate Immune Signaling and Alcohol Use Disorders
  27. Altmetric Badge
    Chapter 194 Correction to: Transcriptional Regulators as Targets for Alcohol Pharmacotherapies
Attention for Chapter 86: Corticotropin-Releasing Factor (CRF) Neurocircuitry and Neuropharmacology in Alcohol Drinking
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Chapter title
Corticotropin-Releasing Factor (CRF) Neurocircuitry and Neuropharmacology in Alcohol Drinking
Chapter number 86
Book title
The Neuropharmacology of Alcohol
Published in
Handbook of experimental pharmacology, January 2018
DOI 10.1007/164_2017_86
Pubmed ID
Book ISBNs
978-3-31-996522-2, 978-3-31-996523-9
Authors

Allyson L. Schreiber, Nicholas W. Gilpin, Schreiber, Allyson L., Gilpin, Nicholas W.

Abstract

Alcohol use is pervasive in the United States. In the transition from nonhazardous drinking to hazardous drinking and alcohol use disorder, neuroadaptations occur within brain reward and brain stress systems. One brain signaling system that has received much attention in animal models of excessive alcohol drinking and alcohol dependence is corticotropin-releasing factor (CRF). The CRF system is composed of CRF, the urocortins, CRF-binding protein, and two receptors - CRF type 1 and CRF type 2. This review summarizes how acute, binge, and chronic alcohol dysregulates CRF signaling in hypothalamic and extra-hypothalamic brain regions and how this dysregulation may contribute to changes in alcohol reinforcement, excessive alcohol consumption, symptoms of negative affect during withdrawal, and alcohol relapse. In addition, it summarizes clinical work examining CRF type 1 receptor antagonists in humans and discusses why the brain CRF system is still relevant in alcohol research.

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X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 47 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 6 13%
Student > Ph. D. Student 6 13%
Student > Bachelor 4 9%
Other 3 6%
Professor 3 6%
Other 5 11%
Unknown 20 43%
Readers by discipline Count As %
Neuroscience 10 21%
Biochemistry, Genetics and Molecular Biology 3 6%
Medicine and Dentistry 3 6%
Agricultural and Biological Sciences 2 4%
Psychology 1 2%
Other 3 6%
Unknown 25 53%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 February 2018.
All research outputs
#14,374,036
of 23,018,998 outputs
Outputs from Handbook of experimental pharmacology
#356
of 647 outputs
Outputs of similar age
#240,496
of 442,354 outputs
Outputs of similar age from Handbook of experimental pharmacology
#10
of 23 outputs
Altmetric has tracked 23,018,998 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 647 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 442,354 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.