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The Neuropharmacology of Alcohol

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Cover of 'The Neuropharmacology of Alcohol'

Table of Contents

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    Book Overview
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    Chapter 76 Presynaptic Ethanol Actions: Potential Roles in Ethanol Seeking
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    Chapter 77 Ethanol and Cytokines in the Central Nervous System
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    Chapter 78 Voltage-Sensitive Potassium Channels of the BK Type and Their Coding Genes Are Alcohol Targets in Neurons
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    Chapter 79 Advances in Pharmacotherapy Development: Human Clinical Studies
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    Chapter 80 GABA A Receptor Subtype Mechanisms and the Abuse-Related Effects of Ethanol: Genetic and Pharmacological Evidence
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    Chapter 82 Dynamic Adaptation in Neurosteroid Networks in Response to Alcohol
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    Chapter 85 Advancing Pharmacotherapy Development from Preclinical Animal Studies
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    Chapter 86 Corticotropin-Releasing Factor (CRF) Neurocircuitry and Neuropharmacology in Alcohol Drinking
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    Chapter 88 Hepatic Immune System: Adaptations to Alcohol
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    Chapter 89 Molecular, Neuronal, and Behavioral Effects of Ethanol and Nicotine Interactions
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    Chapter 90 Chronic Alcohol, Intrinsic Excitability, and Potassium Channels: Neuroadaptations and Drinking Behavior
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    Chapter 92 Innate Immune Signaling and Alcohol Use Disorders
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    Chapter 93 Voltage-Sensitive Calcium Channels in the Brain: Relevance to Alcohol Intoxication and Withdrawal
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    Chapter 98 GABA and Glutamate Synaptic Coadaptations to Chronic Ethanol in the Striatum
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    Chapter 100 Contribution of Dynorphin and Orexin Neuropeptide Systems to the Motivational Effects of Alcohol
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    Chapter 101 Transcriptional Regulators as Targets for Alcohol Pharmacotherapies
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    Chapter 105 Do Alcohol-Related AMPA-Type Glutamate Receptor Adaptations Promote Intake?
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    Chapter 106 Cross-Species Alterations in Synaptic Dopamine Regulation After Chronic Alcohol Exposure
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    Chapter 108 Central Noradrenergic Interactions with Alcohol and Regulation of Alcohol-Related Behaviors
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    Chapter 109 The Cerebellar GABA A R System as a Potential Target for Treating Alcohol Use Disorder
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    Chapter 189 Correction to: Presynaptic Ethanol Actions: Potential Roles in Ethanol Seeking
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    Chapter 190 Correction to: GABA A Receptor Subtype Mechanisms and the Abuse-Related Effects of Ethanol: Genetic and Pharmacological Evidence
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    Chapter 191 Correction to: Advancing Pharmacotherapy Development from Preclinical Animal Studies
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    Chapter 192 Correction to: Chronic Alcohol, Intrinsic Excitability, and Potassium Channels: Neuroadaptations and Drinking Behavior
  26. Altmetric Badge
    Chapter 193 Correction to: Innate Immune Signaling and Alcohol Use Disorders
  27. Altmetric Badge
    Chapter 194 Correction to: Transcriptional Regulators as Targets for Alcohol Pharmacotherapies
Attention for Chapter 98: GABA and Glutamate Synaptic Coadaptations to Chronic Ethanol in the Striatum
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Chapter title
GABA and Glutamate Synaptic Coadaptations to Chronic Ethanol in the Striatum
Chapter number 98
Book title
The Neuropharmacology of Alcohol
Published in
Handbook of experimental pharmacology, January 2018
DOI 10.1007/164_2018_98
Pubmed ID
Book ISBNs
978-3-31-996522-2, 978-3-31-996523-9
Authors

Verginia C. Cuzon Carlson

Abstract

Alcohol (ethanol) is a widely used and abused drug with approximately 90% of adults over the age of 18 consuming alcohol at some point in their lifetime. Alcohol exerts its actions through multiple neurotransmitter systems within the brain, most notably the GABAergic and glutamatergic systems. Alcohol's actions on GABAergic and glutamatergic neurotransmission have been suggested to underlie the acute behavioral effects of ethanol. The striatum is the primary input nucleus of the basal ganglia that plays a role in motor and reward systems. The effect of ethanol on GABAergic and glutamatergic neurotransmission within striatal circuitry has been thought to underlie ethanol taking, seeking, withdrawal and relapse. This chapter reviews the effects of ethanol on GABAergic and glutamatergic transmission, highlighting the dynamic changes in striatal circuitry from acute to chronic exposure and withdrawal.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 16%
Student > Master 2 11%
Student > Bachelor 2 11%
Student > Doctoral Student 1 5%
Other 1 5%
Other 5 26%
Unknown 5 26%
Readers by discipline Count As %
Neuroscience 6 32%
Agricultural and Biological Sciences 2 11%
Biochemistry, Genetics and Molecular Biology 2 11%
Arts and Humanities 1 5%
Unspecified 1 5%
Other 2 11%
Unknown 5 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 February 2018.
All research outputs
#15,492,327
of 23,023,224 outputs
Outputs from Handbook of experimental pharmacology
#398
of 647 outputs
Outputs of similar age
#269,806
of 442,364 outputs
Outputs of similar age from Handbook of experimental pharmacology
#13
of 23 outputs
Altmetric has tracked 23,023,224 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 647 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
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We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.