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Experimental Cholestasis Research

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Cover of 'Experimental Cholestasis Research'

Table of Contents

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    Book Overview
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    Chapter 1 Mechanisms of Drug-Induced Cholestasis
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    Chapter 2 LC-MS/MS Analysis of Bile Acids in In Vitro Samples
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    Chapter 3 Pipe-3D: A Pipeline Based on Immunofluorescence, 3D Confocal Imaging, Reconstructions, and Morphometry for Biliary Network Analysis in Cholestasis
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    Chapter 4 Vesicle- and Hepatocyte-Based Assays for Identification of Drug Candidates Inhibiting BSEP Function
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    Chapter 5 The C-DILI™ Assay: An Integrated In Vitro Approach to Predict Cholestatic Hepatotoxicity
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    Chapter 6 In Vivo Measurement of Hepatic Drug Transporter Inhibition with Radiolabeled Bile Acids
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    Chapter 7 Measuring the Impact of Bile Acids on the Membrane Order of Primary Hepatocytes and Isolated Mitochondria by Fluorescence Imaging and Spectroscopy
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    Chapter 8 The Role and Study of Mitochondrial Impairment and Oxidative Stress in Cholestasis
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    Chapter 9 Measuring Apoptosis and Necrosis in Cholestatic Liver Injury
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    Chapter 10 Necrosome Formation and Necroptosis in Experimental Cholestasis
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    Chapter 11 Proteomics in Primary Biliary Cholangitis
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    Chapter 12 Transcriptomic Analysis of Cholestatic Compounds In Vitro
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    Chapter 13 System Microscopy of Stress Response Pathways in Cholestasis Research
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    Chapter 14 Mouse Models for Diseases in the Cholangiocyte Lineage
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    Chapter 15 Common Bile Duct Ligation as Model for Secondary Biliary Cirrhosis
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    Chapter 16 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine Diet: A Rodent Model in Cholestasis Research
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    Chapter 17 A Rotavirus-Induced Mouse Model to Study Biliary Atresia and Neonatal Cholestasis
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    Chapter 18 Zebrafish as a Model to Study Cholestatic Liver Diseases
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    Chapter 19 Setup and Use of HepaRG Cells in Cholestasis Research
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    Chapter 20 Organotypic 3D HepaRG Liver Model for Assessment of Drug-Induced Cholestasis
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    Chapter 21 Establishment of Sandwich Cultures of Primary Human Hepatocytes
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    Chapter 22 Detection of Drug-Induced Cholestasis Potential in Sandwich-Cultured Human Hepatocytes
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    Chapter 23 Ex Vivo Model in Cholestasis Research
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    Chapter 24 Patient-Derived Organoids from Human Bile: An In Vitro Method to Study Cholangiopathies
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    Chapter 25 Use of Biliary Organoids in Cholestasis Research
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    Chapter 26 In Silico Approaches to Predict Drug-Transporter Interaction Profiles: Data Mining, Model Generation, and Link to Cholestasis
Attention for Chapter 11: Proteomics in Primary Biliary Cholangitis
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