@HermanPontzer @KevinH_PhD @iaeaorg Interesting discussion! https://t.co/YMSg2C5dVp https://t.co/8VdLqUOWF1
@MatthewJDalby @deirdre_tobias BTW, we measured RQ using respiratory chambers simultaneous to DLW periods during keto vs baseline diets which showed how important the RQ effect can be: https://t.co/ehcPjgpbVO
@johnzahorik That's one possible interpretation, but remember that these diets were not isocaloric. Our previous studies don't support a substantial "metabolic advantage" of ketogenic diets: https://t.co/S90PUkvIP0 https://t.co/QKW7kxdRVD https://t.co/pfvZ
However, exploratory doubly labeled water (DLW) measurements appeared to indicate greater EE during the keto diet. We later realized this was an artifact of incorrect respiratory quotient (RQ) assumptions in the DLW calculations during non-chamber periods: